Three new software systems, Ingenuity pathway analysis (IPA, TranscriptomeBrowser and
MetaCore, were compared by analyzing chondrocyte microarray data of Kashin–Beck …

Objectives: Primary osteoarthritis (OA) and Kashin–Beck disease (KBD) exhibit similar
clinical manifestations and common articular cartilage lesions. Revealing the pathogenetic …

Kashin–beck disease (KBD) is endemic chronic osteoarthrosis and its pathogenesis is still
unclear. The present study aimed to explore differential gene expression in articular …

Aims To understand the pathogenesis of cartilage damage in Kashin–Beck disease (KBD)
and rheumatoid arthritis (RA) which similar clinical symptoms. Methods RNA sequencing …

Kashin-Beck disease (KBD) is a chronic osteochondropathy. The pathogenesis of KBD
remains unknown. To identify relevant biological pathways for KBD, we conducted a …

Abstract Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of
unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar …

The pathological mechanism of Kashin-Beck disease (KBD), an endemic osteoarthritic
disease, remains to be poorly understood. This study was designed to identify signaling …

Kashin-Beck disease (KBD) is an endemic, degenerative osteoarthropathy that exhibits
some similar characteristics to osteoarthritis (OA) but with different etiologies and …

This investigation was designed to unravel gene networks in K ashin–B eck disease (KBD)
and better identify target genes of KBD for gene therapy development. RNA was isolated …

Objective To investigate the differences in gene expression profiles of adult articular
cartilage from patients with Kashin‐Beck disease (KBD) versus those with primary knee …