[HTML][HTML] Association of oxidative stress and Kashin–Beck disease integrated Meta and Bioinformatics analysis

Y Ba, L Sun, J Zuo, SY Yu, S Yang, LM Ding… - Osteoarthritis and …, 2022 - Elsevier
Objective To explore the association between oxidative stress (OS) and Kashin-Beck
disease (KBD). Methods Terms associated with “KBD” and “OS” were searched in the six …

[HTML][HTML] Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis

WZ Wang, X Guo, C Duan, WJ Ma, YG Zhang… - Osteoarthritis and …, 2009 - Elsevier
OBJECTIVE: To investigate the differences in gene expression profiles of adult articular
cartilage with endemic osteoarthritis (OA), Kashin–Beck disease (KBD), and the same …

Identification of diagnostic biomarkers of osteoarthritis based on multi-chip integrated analysis and machine learning

Y Zhang, Y Yang, C Wang, S Wan, Z Yao… - DNA and Cell …, 2020 - liebertpub.com
The pathogenesis of osteoarthritis (OA) is still unclear. It is therefore important to identify
relevant diagnostic marker genes for OA. We performed an integrated analysis with multiple …

[HTML][HTML] Identification of key candidate genes and pathways in rheumatoid arthritis and osteoarthritis by integrated bioinformatical analysis

H Huang, X Dong, K Mao, W Pan, B Nie… - Frontiers in Genetics, 2023 - frontiersin.org
Rheumatoid arthritis (RA) and osteoarthritis (OA) are the most common joint disorders.
Although they have shown analogous clinical manifestations, the pathogenesis of RA and …

Genetic association scan of 32 osteoarthritis susceptibility genes identified TP63 associated with an endemic osteoarthritis, Kashin-Beck disease

B Cheng, C Liang, X Yang, P Li, L Liu, S Cheng, Y Jia… - Bone, 2021 - Elsevier
Abstract Background Kashin-Beck disease (KBD) is an endemic chronic osteochondropathy.
The clinical manifestations and radiographic features of adult KBD were similar to those of …

A preliminary analysis of microRNA profiles in the subchondral bone between Kashin-Beck disease and primary knee osteoarthritis

GH Zhao, L Yang, MJ Lammi, X Guo - Clinical rheumatology, 2019 - Springer
Abstract Introduction Kashin-Beck disease (KBD) is a chronic osteochondral disorder
primarily associated with cartilage degeneration. The bone texture structure in KBD was also …

[HTML][HTML] Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis

W Wu, A He, Y Wen, X Xiao, J Hao, F Zhang, X Guo - Scientific reports, 2017 - nature.com
Kashin-Beck disease (KBD) is a chronic osteochondropathy with unclear pathogeny. In this
study, we compared the microRNA expression profiles of 16 KBD patients, 16 osteoarthritis …

[HTML][HTML] Abnormal expression of chondroitin sulphate N-acetylgalactosaminyltransferase 1 and Hapln-1 in cartilage with Kashin–Beck disease and primary …

J Zheng, C Wu, W Ma, Y Zhang, T Hou, H Xu… - International …, 2013 - Springer
Abstract Purpose Kashin-Beck disease (KBD) is an endemic degenerative osteoarthritis
associated with extracellular matrix degradation. The aim of this investigation was to …

[HTML][HTML] Comparative analysis of signaling pathways in peripheral blood from patients with Kashin‑Beck disease and osteoarthritis

Y Ning, X Wang, S Wang, X Guo - Experimental and …, 2016 - spandidos-publications.com
The aim of the present study was to investigate the early diagnostic biomarkers of Kashin‑
Beck disease (KBD), and to compare the common signaling pathways of peripheral …

Identification and molecular mechanisms study of genes associated with osteoarthritis: a comprehensive bioinformatic study of cartilage and synovium

S Li, X Wang, J Li, W Wei, J Liu - Critical Reviews™ in …, 2022 - dl.begellhouse.com
Osteoarthritis (OA) is a severe disease and has brought a massive burden to people's daily
life. This study was performed to explore the hub genes associated with OA and predict …