Effect of nebivolol on renal nitric oxide availability and tubular function in patients with essential hypertension
FH Mose, JM Jensen, S Therwani… - British Journal of …, 2015 - Wiley Online Library
Aims Nebivolol is a selective β1‐receptor antagonist with vasodilating properties. In patients
with essential hypertension, we tested the hypothesis that nebivolol increases systemic and …
with essential hypertension, we tested the hypothesis that nebivolol increases systemic and …
Nebivolol Ameliorates Nitric Oxide–Deficient Hypertension
LA Fortepiani, MC Ortíz, NM Atucha… - The Scientific World …, 2002 - Wiley Online Library
Nebivolol is a new selective beta 1‐adrenoceptor antagonist with nitric oxide (NO)–
releasing properties. In the present study we have analyzed whether nebivolol affects the …
releasing properties. In the present study we have analyzed whether nebivolol affects the …
The effect of nebivolol and atenolol on renal and systemic haemodynamics in hypertensive patients
P Van De Borne, F Fici, W Makel, A Fiasse… - High blood pressure & …, 2007 - Springer
Objectives: Nebivolol is a selective β 1-adrenoceptor antagonist with endothelium-mediated
vasodilating properties. The effects of nebivolol on renal haemodyamics are unknown in …
vasodilating properties. The effects of nebivolol on renal haemodyamics are unknown in …
Characterization of nitric oxide release by nebivolol and its metabolites
A Maffei, C Vecchione, A Aretini… - American journal of …, 2006 - academic.oup.com
Background: Nebivolol is a selective β1-adrenergic receptor antagonist that causes a direct
vasodilator effect attributed to the action on vascular nitric oxide (NO). This study aimed to …
vasodilator effect attributed to the action on vascular nitric oxide (NO). This study aimed to …
Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study
N Tzemos, PO Lim, TM MacDonald - Circulation, 2001 - Am Heart Assoc
Background Vascular endothelial dysfunction may predict future atherosclerosis. Hence, an
antihypertensive agent that reverses endothelial dysfunction and lowers blood pressure …
antihypertensive agent that reverses endothelial dysfunction and lowers blood pressure …
Nitric-oxide-mediated relaxations in salt-induced hypertension: effect of chronic β1-selective receptor blockade
F Cosentino, S Bonetti, R Rehorik, M Eto… - Journal of …, 2002 - journals.lww.com
Background Nebivolol is a new β 1-selective adrenergic receptor antagonist with a direct
vasorelaxant effect that involves activation of the l-arginine–nitric oxide (NO) pathway …
vasorelaxant effect that involves activation of the l-arginine–nitric oxide (NO) pathway …
Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney disease in the rat: a comparison with angiotensin II …
NC Moningka, T Tsarova, JM Sasser… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. Nitric oxide (NO) deficiency contributes to chronic kidney disease (CKD)
progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production …
progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production …
Nitric oxide mechanisms of nebivolol
A Maffei, G Lembo - Therapeutic advances in cardiovascular …, 2009 - journals.sagepub.com
β-blockers are among the most widely used drugs in the prevention and treatment of
cardiovascular disease, although they are associated with increased peripheral resistance …
cardiovascular disease, although they are associated with increased peripheral resistance …
Clinical pharmacodynamics of nebivolol: new evidence of nitric oxide‐mediated vasodilating activity and peculiar haemodynamic properties in hypertensive patients
A Zanchetti - Blood pressure, 2004 - Taylor & Francis
New evidence from recently completed clinical studies performed with nebivolol, a highly
selective beta‐1 β‐blocker, endowed with additional vasodilating activity mediated by nitric …
selective beta‐1 β‐blocker, endowed with additional vasodilating activity mediated by nitric …
Recent advances in the treatment of renal diseases with nebivolol: A literature review
FS Amiri - Néphrologie & Thérapeutique, 2016 - Elsevier
Reactive oxygen species play an important role in both acute and chronic kidney diseases.
Chronic kidney disease is associated with various consequences to the cardiovascular …
Chronic kidney disease is associated with various consequences to the cardiovascular …