New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
Fibroblast growth factors, fibroblast growth factor receptors, diseases, and drugs
GJ Chen, R Forough - Recent Patents on Cardiovascular Drug …, 2006 - ingentaconnect.com
Maintenance of endothelial cells (ECs), the building blocks of the vascular tree, is a
presumed function of fibroblast growth factors (FGFs). In particular, the two prototypic …
presumed function of fibroblast growth factors (FGFs). In particular, the two prototypic …
The fibroblast growth factor signaling pathway
DM Ornitz, N Itoh - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …
Fibroblast growth factors, old kids on the new block
The fibroblast growth factors (FGFs) are a family of cell intrinsic regulatory peptides that
control a broad spectrum of cellular activities. The family includes canonic FGFs that elicit …
control a broad spectrum of cellular activities. The family includes canonic FGFs that elicit …
Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease
N Itoh, DM Ornitz - The Journal of Biochemistry, 2011 - academic.oup.com
Fibroblast growth factors (FGFs) are a family of structurally related polypeptides that are
essential for embryonic development and that function postnatally as homoeostatic factors …
essential for embryonic development and that function postnatally as homoeostatic factors …
Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology
AA Belov, M Mohammadi - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Fibroblast growth factors (FGFs) signal in a paracrine or endocrine fashion to mediate a
myriad of biological activities, ranging from issuing developmental cues, maintaining tissue …
myriad of biological activities, ranging from issuing developmental cues, maintaining tissue …
Isoforms of receptors of fibroblast growth factors
SG Gong - Journal of cellular physiology, 2014 - Wiley Online Library
The breadth and scope of Fibroblast Growth Factor signaling is immense, with
documentation of its role in almost every organism and system studied so far. FGF ligands …
documentation of its role in almost every organism and system studied so far. FGF ligands …
[引用][C] Overview of the fibroblast growth factor and receptor families: complexity, functional diversity, and implications for future cardiovascular research
SE Hughes, PA Hall - Cardiovascular research, 1993 - academic.oup.com
ibroblast growth factors (FGF) constitute a multigene family of seven structurally related
polypeptide growth F factors which mediate their effects by binding to a family of high affinity …
polypeptide growth F factors which mediate their effects by binding to a family of high affinity …
Fibroblast growth factor 2: from laboratory evidence to clinical application
CH Chen, SM Poucher, J Lu… - Current vascular …, 2004 - ingentaconnect.com
Fibroblast growth factor 2 (FGF2) is expressed ubiquitously in mesodermal and
neuroectodermal cells. Human FGF2 occurs in isoforms translated from a common mRNA by …
neuroectodermal cells. Human FGF2 occurs in isoforms translated from a common mRNA by …
Fibroblast growth factors as multifunctional signaling factors
G Szebenyi, JF Fallon - International review of cytology, 1998 - Elsevier
The fibroblast growth factor (FGF) family consists of at least 15 structurally related
polypeptide growth factors. Their expression is controlled at the levels of transcription …
polypeptide growth factors. Their expression is controlled at the levels of transcription …