The incidence of type 2 diabetes (T2D) has rapidly increased over recent decades, and T2D
has become a leading public health challenge in China. Compared with European …

Abstract Purpose of Review Genome-wide association studies have delineated the genetic
architecture of type 2 diabetes. While functional studies to identify target transcripts are …

Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …

With rapidly increasing prevalence, diabetes has become one of the major causes of
mortality worldwide. According to the latest studies, genetic information makes substantial …

The global epidemic of type 2 diabetes mellitus (T2D) is one of the most challenging
problems of the 21 st century leading cause of and the fifth death worldwide. Substantial …

Type 2 diabetes (T2D) had long been referred to as the" geneticist's nightmare." Genome-
wide association studies have fully confirmed the polygenic nature of T2D, demonstrating …

BACKGROUND Type 2 diabetes (T2D) is a complex disorder that is affected by multiple
genetic and environmental factors. Extensive efforts have been made to identify the disease …

Abstract Knowledge of the genetics of type 2 diabetes mellitus (T2DM) has evolved
tremendously over the past few years. Following advances in technology and analytical …

OBJECTIVE Type 2 diabetes (T2D) was recently reclassified into severe insulin-deficient
diabetes (SIDD), severe insulin-resistant diabetes (SIRD), mild obesity-related diabetes …

The elucidation of several genetic etiologies of both monogenic and polygenic type 2
diabetes (T2D) has revealed several key regulators of glucose homeostasis and insulin …