Epidermal growth factor receptor kinase activity is required for gap junction closure and for part of the decrease in ovarian follicle cGMP in response to LH
The meiotic cell cycle in mouse oocytes is arrested in prophase, and then restarted when LH
acts on the surrounding granulosa cells. The granulosa cells keep meiosis arrested by …
acts on the surrounding granulosa cells. The granulosa cells keep meiosis arrested by …
Mouse oocyte maturation: meiotic checkpoints
J Fulka Jr, RM Moor, J Fulka - Experimental cell research, 1995 - Elsevier
Mouse oocytes at different stages of maturation were fused together and the ensuing cell
cycle events were analyzed with the objective of identifying checkpoints in meiosis. Fusion …
cycle events were analyzed with the objective of identifying checkpoints in meiosis. Fusion …
Regulation of mouse oocyte meiotic maturation: implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis
RM Schultz, RR Montgomery, JR Belanoff - Developmental biology, 1983 - Elsevier
Mouse oocytes are reversibly inhibited from resuming meiotic maturation in vitro by cAMP
phosphodiesterase inhibitors such as 3-isobutyl-1-methyl xanthine (IBMX) and cAMP …
phosphodiesterase inhibitors such as 3-isobutyl-1-methyl xanthine (IBMX) and cAMP …
Cellular, biochemical and molecular mechanisms regulating oocyte maturation
N Dekel - Molecular and cellular endocrinology, 2005 - Elsevier
The original model for regulation of oocyte maturation proposed by us in 1978 postulated
that gap junction-mediated transmission of cAMP from the follicle cells to the oocyte inhibits …
that gap junction-mediated transmission of cAMP from the follicle cells to the oocyte inhibits …
Acquisition of meiotic competence is related to the functionality of the phosphoinositide/calcium signaling pathway in the mouse oocyte
B Lefèvre, E Nagyova, A Pesty, J Testart - Experimental cell research, 1997 - Elsevier
The meiosis resumption process has been related to spontaneous cytoplasmic InsP3-
dependent calcium oscillations in fully grown mouse oocytes. Our purpose was to determine …
dependent calcium oscillations in fully grown mouse oocytes. Our purpose was to determine …
Androgenic modulation of cyclic adenosine monophosphate (cAMP)-dependent meiotic arrest
C Racowsky - Biology of reproduction, 1983 - academic.oup.com
This study investigated further our previous finding that testosterone synergizes with
dibutyryl cyclic AMP (dbcAMP) to arrest the meiosis of a very high proportion of cumulus …
dibutyryl cyclic AMP (dbcAMP) to arrest the meiosis of a very high proportion of cumulus …
[HTML][HTML] Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional …
Prior to birth, oocytes within mammalian ovarian follicles initiate meiosis, but then arrest in
prophase until puberty, when with each reproductive cycle, one or more follicles are …
prophase until puberty, when with each reproductive cycle, one or more follicles are …
Protein kinase C and meiotic regulation in isolated mouse oocytes
SM Downs, J Cottom… - Molecular reproduction …, 2001 - Wiley Online Library
In this study, the possible role of protein kinase C (PKC) in mediating both positive and
negative actions on meiotic maturation in isolated mouse oocytes has been examined …
negative actions on meiotic maturation in isolated mouse oocytes has been examined …
Knockdown of the cAMP‐dependent protein kinase (PKA) Type Iα regulatory subunit in mouse oocytes disrupts meiotic arrest and results in meiotic spindle defects
FE Duncan, SB Moss, CJ Williams - Developmental dynamics, 2006 - Wiley Online Library
In mammalian oocytes, cyclic AMP‐dependent protein kinase (PKA) is responsible for
maintaining meiotic arrest. We examined the role of the predominant regulatory subunit, RIα …
maintaining meiotic arrest. We examined the role of the predominant regulatory subunit, RIα …
Meiotic induction by heat stress in mouse oocytes: involvement of AMP-activated protein kinase and MAPK family members
C LaRosa, SM Downs - Biology of reproduction, 2007 - academic.oup.com
In this study, we examined the effect of heat pulsing on oocyte maturation and assessed the
possible role of stress-activated enzymes during heat stress-induced meiotic maturation …
possible role of stress-activated enzymes during heat stress-induced meiotic maturation …