Epidermal growth factor receptor kinase activity is required for gap junction closure and for part of the decrease in ovarian follicle cGMP in response to LH

RP Norris, M Freudzon, VO Nikolaev, LA Jaffe - Reproduction, 2010 - rep.bioscientifica.com
The meiotic cell cycle in mouse oocytes is arrested in prophase, and then restarted when LH
acts on the surrounding granulosa cells. The granulosa cells keep meiosis arrested by …

Mouse oocyte maturation: meiotic checkpoints

J Fulka Jr, RM Moor, J Fulka - Experimental cell research, 1995 - Elsevier
Mouse oocytes at different stages of maturation were fused together and the ensuing cell
cycle events were analyzed with the objective of identifying checkpoints in meiosis. Fusion …

Regulation of mouse oocyte meiotic maturation: implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis

RM Schultz, RR Montgomery, JR Belanoff - Developmental biology, 1983 - Elsevier
Mouse oocytes are reversibly inhibited from resuming meiotic maturation in vitro by cAMP
phosphodiesterase inhibitors such as 3-isobutyl-1-methyl xanthine (IBMX) and cAMP …

Cellular, biochemical and molecular mechanisms regulating oocyte maturation

N Dekel - Molecular and cellular endocrinology, 2005 - Elsevier
The original model for regulation of oocyte maturation proposed by us in 1978 postulated
that gap junction-mediated transmission of cAMP from the follicle cells to the oocyte inhibits …

Acquisition of meiotic competence is related to the functionality of the phosphoinositide/calcium signaling pathway in the mouse oocyte

B Lefèvre, E Nagyova, A Pesty, J Testart - Experimental cell research, 1997 - Elsevier
The meiosis resumption process has been related to spontaneous cytoplasmic InsP3-
dependent calcium oscillations in fully grown mouse oocytes. Our purpose was to determine …

Androgenic modulation of cyclic adenosine monophosphate (cAMP)-dependent meiotic arrest

C Racowsky - Biology of reproduction, 1983 - academic.oup.com
This study investigated further our previous finding that testosterone synergizes with
dibutyryl cyclic AMP (dbcAMP) to arrest the meiosis of a very high proportion of cumulus …

[HTML][HTML] Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional …

JR Egbert, SP Yee, LA Jaffe - Developmental biology, 2018 - Elsevier
Prior to birth, oocytes within mammalian ovarian follicles initiate meiosis, but then arrest in
prophase until puberty, when with each reproductive cycle, one or more follicles are …

Protein kinase C and meiotic regulation in isolated mouse oocytes

SM Downs, J Cottom… - Molecular reproduction …, 2001 - Wiley Online Library
In this study, the possible role of protein kinase C (PKC) in mediating both positive and
negative actions on meiotic maturation in isolated mouse oocytes has been examined …

Knockdown of the cAMP‐dependent protein kinase (PKA) Type Iα regulatory subunit in mouse oocytes disrupts meiotic arrest and results in meiotic spindle defects

FE Duncan, SB Moss, CJ Williams - Developmental dynamics, 2006 - Wiley Online Library
In mammalian oocytes, cyclic AMP‐dependent protein kinase (PKA) is responsible for
maintaining meiotic arrest. We examined the role of the predominant regulatory subunit, RIα …

Meiotic induction by heat stress in mouse oocytes: involvement of AMP-activated protein kinase and MAPK family members

C LaRosa, SM Downs - Biology of reproduction, 2007 - academic.oup.com
In this study, we examined the effect of heat pulsing on oocyte maturation and assessed the
possible role of stress-activated enzymes during heat stress-induced meiotic maturation …