This article reports on the synthesis and full characterization of innovative silica-based
nanoparticle composed of fumed silica as a core decorated with polyethylenimine (PEI) with …

Organic-inorganic hybrid silica nanoparticles (PM-1, PM-2 and PM-3) with positive surface
charge and size below 200 nm were one-pot prepared viaMichael addition between 3 …

The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …

Nanoparticles have an enormous potential for development in biomedical applications, such
as gene or drug delivery. We developed and characterized aminopropyltriethoxysilane …

Due to large surface area, tunable pore size, easy surface manipulation, and low-toxicity
mesoporous silica nanoparticles (MSNs) may act as a suitable vector for gene delivery. In …

Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …

Limitation of tumor vascularization can be helpful for cancer treatment. Silica nanoparticles
can be produced in small diameters with good reproducibility, stability, and biocompatibility …

In order to develop a safe and effective gene therapy carrier, some toxicological and
biodynamical experiments were carried out on silica nanoparticles (SiNPs). First we …

Cellular delivery of DNA using silica nanoparticles has attracted great attention. Typically,
polyethyleneimine (PEI) is used to form a silica/PEI composite vector. Understanding the …

The present paper reports the utilization of hybrid nanocomposite particles consisting of
PEI25k-PEG5k copolymer grafted silica nanoparticles (SiO 2 NPs) for enhanced cellular …