IL24 is an immunomodulatory cytokine that also displays broad cancer-specific suppressor
effects. The tumor-suppressor activities of IL24 include inhibition of angiogenesis …

Dysregulated activity of helicase eIF4A drives transformation to and maintenance of cancer
cell phenotype by reprogramming cellular translation. Interleukin 24 (IL-24) is a tumor …

The eukaryotic initiation factor 3f (eIF3f) is the p47 subunit of the multi-subunit eIF3 complex.
eIF3 plays an important role in translation initiation. In the present study, we investigate the …

Eukaryotic translation initiation factor 5A (eIF5A) is thought to function as a
nucleocytoplasmic shuttle protein. There are reports of its involvement in cell proliferation …

Physiological stress conditions attenuate global mRNA translation via modifications of key
eukaryotic initiation factors. However, non-canonical translation initiation mechanisms allow …

Eukaryotic translation initiation factor 6 (eIF6) affects the maturation of 60S ribosomal
subunits. Found in yeast and mammalian cells, eIF6 is primarily located in the cytoplasm of …

Translation has important roles in almost all physiological and pathological processes, and
translation initiation factors are particularly relevant to the translation initiation step, which is …

Summary Eukaryotic Initiation Factor 6 (eIF6) controls translation by regulating 80S subunit
formation. eIF6 is overexpressed in tumors. Here, we demonstrate that eIF6 inactivation …

Translational control (TC) is one the crucial steps that dictate gene expression and alter the
outcome of physiological process like programmed cell death, metabolism, and proliferation …

Objectives Eukaryotic translation initiation factor 3 (eIF3) is a multi-subunit complex that
plays a critical role in translation initiation. Expression levels of eIF3 subunits are elevated or …