Carboxylesterases (CE) are ubiquitous enzymes found in both human and animal tissues
and are responsible for the metabolism of xenobiotics. This includes numerous natural …

Carboxylesterases (CE) are ubiquitous enzymes responsible for the metabolism of
xenobiotics. Because the structural and amino acid homology among esterases of different …

Carboxylesterase type 1 (CES1) and CES2 are serine hydrolases located in the liver and
small intestine. CES1 and CES2 actively participate in the metabolism of several …

Human carboxylesterase 1 (hCE1), one of the most important serine hydrolases distributed
in liver and adipocytes, plays key roles in endobiotic homeostasis and xenobiotic …

Human carboxylesterase 1 (hCE-1, CES1A1, HU1) and carboxylesterase 2 (hCE-2, hiCE,
HU3) are a serine esterase involved in both drug metabolism and activation. Although both …

Esterases catalyze the hydrolysis of therapeutic drugs containing esters or amides in their
structures. Human carboxylesterase (CES) and arylacetamide deacetylase (AADAC) are the …

Purpose To predict and determine whether the protease inhibitors (PIs) nelfinavir,
amprenavir, atazanavir, ritonavir, and saquinavir could serve as metabolic inhibitors of the …

Carboxylesterases (CES, EC 3.1. 1.1) are members of a superfamily of serine hydrolases
that hydrolyze ester, amide, and carbamate bonds. Several different CES genes exist in …

Carboxylesterases belong to Phase I group of drug metabolizing enzymes. They hydrolyze a
variety of drug esters, amides, carbamates and similar structures. There are five …

Carboxylesterases (CES, EC 3.1. 1.1) hydrolyze ester, amide, and carbamate bonds found
in xenobiotics and endobiotics. Multiple CES genes exist in mammals with evidence of …