[HTML][HTML] Dyslexia risk gene relates to representation of sound in the auditory brainstem
Dyslexia is a reading disorder with strong associations with KIAA0319 and DCDC2. Both
genes play a functional role in spike time precision of neurons. Strikingly, poor readers show …
genes play a functional role in spike time precision of neurons. Strikingly, poor readers show …
Knockdown of the Dyslexia-Associated Gene Kiaa0319 Impairs Temporal Responses to Speech Stimuli in Rat Primary Auditory Cortex
TM Centanni, AB Booker, AM Sloan, F Chen… - Cerebral …, 2014 - academic.oup.com
One in 15 school age children have dyslexia, which is characterized by phoneme-
processing problems and difficulty learning to read. Dyslexia is associated with mutations in …
processing problems and difficulty learning to read. Dyslexia is associated with mutations in …
Genetic dyslexia risk variant is related to neural connectivity patterns underlying phonological awareness in children
Phonological awareness is the best-validated predictor of reading and spelling skill and
therefore highly relevant for developmental dyslexia. Prior imaging genetics studies link …
therefore highly relevant for developmental dyslexia. Prior imaging genetics studies link …
[HTML][HTML] A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene
Numerous genetic association studies have implicated the KIAA0319 gene on human
chromosome 6p22 in dyslexia susceptibility. The causative variant (s) remains unknown but …
chromosome 6p22 in dyslexia susceptibility. The causative variant (s) remains unknown but …
[HTML][HTML] Auditory brainstem measures and genotyping boost the prediction of literacy: A longitudinal study on early markers of dyslexia
Literacy acquisition is impaired in children with developmental dyslexia resulting in lifelong
struggle to read and spell. Proper diagnosis is usually late and commonly achieved after …
struggle to read and spell. Proper diagnosis is usually late and commonly achieved after …
Brain responses to changes in speech sound durations differ between infants with and without familial risk for dyslexia
PHT Leppänen, U Richardson, E Pihko… - Developmental …, 2002 - Taylor & Francis
A specific learning disability, developmental dyslexia, is a language-based disorder that is
shown to be strongly familial. Therefore, infants born to families with a history of the disorder …
shown to be strongly familial. Therefore, infants born to families with a history of the disorder …
[HTML][HTML] Increased variability of stimulus-driven cortical responses is associated with genetic variability in children with and without dyslexia
Individuals with dyslexia exhibit increased brainstem variability in response to sound. It is
unknown as to whether increased variability extends to neocortical regions associated with …
unknown as to whether increased variability extends to neocortical regions associated with …
Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory …
LG Guidi, J Mattley, I Martinez-Garay… - Cerebral …, 2017 - academic.oup.com
Developmental dyslexia is a neurodevelopmental disorder that affects reading ability
caused by genetic and non-genetic factors. Amongst the susceptibility genes identified to …
caused by genetic and non-genetic factors. Amongst the susceptibility genes identified to …
[HTML][HTML] The dyslexia candidate locus on 2p12 is associated with general cognitive ability and white matter structure
Independent studies have shown that candidate genes for dyslexia and specific language
impairment (SLI) impact upon reading/language-specific traits in the general population. To …
impairment (SLI) impact upon reading/language-specific traits in the general population. To …
[HTML][HTML] Opposite Associations between Individual KIAA0319 Polymorphisms and Developmental Dyslexia Risk across Populations: A Stratified Meta-Analysis by the …
S Shao, Y Niu, X Zhang, R Kong, J Wang, L Liu… - Scientific Reports, 2016 - nature.com
KIAA0319 at the DYX2 locus is one of the most extensively studied candidate genes for
developmental dyslexia (DD) owing to its important role in neuronal migration. Previous …
developmental dyslexia (DD) owing to its important role in neuronal migration. Previous …