Structure of staphylococcal enterotoxin N: Implications for binding properties to its cellular proteins
C Zeng, Z Liu, Z Han - International Journal of Molecular Sciences, 2019 - mdpi.com
Staphylococcus aureus strains produce a unique family of immunostimulatory exotoxins
termed as bacterial superantigens (SAgs), which cross-link major histocompatibility complex …
termed as bacterial superantigens (SAgs), which cross-link major histocompatibility complex …
Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T‐cell receptor Vβ8. 2
MM Fernández, S Bhattacharya… - PROTEINS …, 2007 - Wiley Online Library
The illnesses associated with bacterial superantigens (SAgs) such as food poisoning and
toxic shock syndrome, as well as the emerging threat of purpura fulminans and community …
toxic shock syndrome, as well as the emerging threat of purpura fulminans and community …
Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor β chain
MM Fernández, S Cho, MC De Marzi, MC Kerzic… - Journal of biological …, 2011 - ASBMB
Superantigens (SAgs) are bacterial or viral toxins that bind MHC class II (MHC-II) molecules
and T-cell receptor (TCR) in a nonconventional manner, inducing T-cell activation that leads …
and T-cell receptor (TCR) in a nonconventional manner, inducing T-cell activation that leads …
Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin J can use a common binding surface for T-cell receptor binding and dimerization
The protein toxins known as superantigens (SAgs), which are expressed primarily by the
pathogenic bacteria Staphylococcus aureus and Streptococcus pyogenes, are highly potent …
pathogenic bacteria Staphylococcus aureus and Streptococcus pyogenes, are highly potent …
Staphylococcal and Streptococcal Superantigens: Basic Biology of Conserved Protein Toxins
EA Larkin, T Krakauer, RG Ulrich… - The Open Toxinology …, 2010 - benthamopen.com
Staphylococcus aureus and Streptococcus pyogenes are gram-positive bacteria that
possess great pathogenic potential in humans, causing numerous maladies such as …
possess great pathogenic potential in humans, causing numerous maladies such as …
A novel loop domain in superantigens extends their T cell receptor recognition site
Superantigens (SAGs) interact with host immune receptors to induce a massive release of
inflammatory cytokines that can lead to toxic shock syndrome and death. Bacterial SAGs can …
inflammatory cytokines that can lead to toxic shock syndrome and death. Bacterial SAGs can …
Allergy—A New Role for T Cell Superantigens of Staphylococcus aureus?
Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …
known. They stimulate large fractions of T cells by cross-linking their T cell receptor with …
Superantigens, a paradox of the immune response
S Noli Truant, DM Redolfi, MB Sarratea, EL Malchiodi… - Toxins, 2022 - mdpi.com
Staphylococcal enterotoxins are a wide family of bacterial exotoxins with the capacity to
activate as much as 20% of the host T cells, which is why they were called superantigens …
activate as much as 20% of the host T cells, which is why they were called superantigens …
Engineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of disease
DM Mattis, AR Spaulding… - … , Design & Selection, 2013 - academic.oup.com
Superantigens (SAgs) are a class of immunostimulatory exotoxins that activate large
numbers of T cells, leading to overproduction of cytokines and subsequent inflammatory …
numbers of T cells, leading to overproduction of cytokines and subsequent inflammatory …
[HTML][HTML] Staphylococcal superantigens in colonization and disease
SX Xu, JK McCormick - Frontiers in cellular and infection microbiology, 2012 - frontiersin.org
Superantigens (SAgs) are a family of potent immunostimulatory exotoxins known to be
produced by only a few bacterial pathogens, including Staphylococcus aureus. More than …
produced by only a few bacterial pathogens, including Staphylococcus aureus. More than …