Background. Microsimulation models are important decision support tools for screening.
However, their complexity makes them difficult to understand and limits realization of their …

Background. Microsimulation models synthesize evidence about disease processes and
interventions, providing a method for predicting long-term benefits and harms of prevention …

Microsimulation models are often used to predict long-term outcomes and guide policy
decisions regarding cancer screening. The United Kingdom Flexible Sigmoidoscopy …

Background Colorectal cancer (CRC) is a leading cause of cancer-related mortality. CRC
incidence and mortality can be reduced by several screening strategies, including …

Simulation models are a powerful tool to overcome gaps of evidence needed to inform
medical decision‐making. Here, we present development and application of COSIMO, a …

Abstract Background: The Colorectal Cancer Simulated Population model for Incidence and
Natural history (CRC-SPIN) is a new microsimulation model for the natural history of …

Background The economic evaluation of colorectal cancer screening is challenging
because of the need to model the underlying unobservable natural history of the disease …

Background. As the complexity of microsimulation models increases, concerns about model
transparency are heightened. Methods. The authors conducted model “experiments” to …

Background. Microsimulation models are increasingly being used to inform colorectal
cancer (CRC) screening recommendations. MISCAN-Colon is an example of such a model …

Background. This study aimed to assess the validity of 2 microsimulation models of
colorectal cancer (CRC), Policy1-Bowel and ASCCA. Methods. The model-estimated CRC …