Background Large-scale genomic studies of within-host diversity in Staphylococcus aureus
bacteraemia (SAB) are needed to understanding bacterial adaptation underlying …

During severe infections, Staphylococcus aureus moves from its colonising sites to blood
and tissues and is exposed to new selective pressures, thus, potentially driving adaptive …

Background Staphylococcus aureus is a human pathogen responsible for substantial
morbidity and mortality through its ability to cause a number of human infections including …

Highlights•Whole-genome sequencing has enabled real-time genomic surveillance of S.
aureus.•Of the 40,000 available S. aureus genomes in NCBI only 0.4% are fully …

Staphylococcus aureus is an important nosocomial and community-acquired pathogen. Its
genetic plasticity has facilitated the evolution of many virulent and drug-resistant strains …

Whole-genome sequencing offers new insights into the evolution of bacterial pathogens and
the etiology of bacterial disease. Staphylococcus aureus is a major cause of bacteria …

Staphylococcus aureus small-colony variants (SCVs) are associated with unusually chronic
and persistent infections despite active antibiotic treatment. The molecular basis for this …

Staphylococcus aureus is a prominent nosocomial pathogen that causes several life-
threatening diseases, such as pneumonia and bacteremia. S. aureus modulates the …

Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a major challenge in
health care, yet the limited heterogeneity within this group hinders molecular investigations …

The diversification of bacterial pathogens during infection is central to their capacity to adapt
to different anatomical niches, evade the host immune system, and overcome therapeutic …