Drivers of methicillin-resistant Staphylococcus aureus (MRSA) lineage replacement in China

H Chen, Y Yin, L van Dorp, LP Shaw, H Gao… - Genome medicine, 2021 - Springer
Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) is a major
nosocomial pathogen subdivided into lineages termed sequence types (STs). Since the …

Genome-Wide Analysis of Ruminant Staphylococcus aureus Reveals Diversification of the Core Genome

NL Ben Zakour, DE Sturdevant, S Even… - Journal of …, 2008 - Am Soc Microbiol
Staphylococcus aureus causes disease in humans and a wide array of animals. Of note, S.
aureus mastitis of ruminants, including cows, sheep, and goats, results in major economic …

Proteomics uncovers extreme heterogeneity in the Staphylococcus aureus exoproteome due to genomic plasticity and variant gene regulation

AK Ziebandt, H Kusch, M Degner, S Jaglitz… - …, 2010 - Wiley Online Library
Sequencing of at least 13 Staphylococcus aureus isolates has shown that genomic plasticity
impacts significantly on the repertoire of virulence factors. However, genome sequencing …

The recombination dynamics of Staphylococcus aureus inferred from spA gene

CD Santos-Júnior, A Veríssimo, J Costa - BMC microbiology, 2016 - Springer
Background Given the role of spA as a pivotal virulence factor decisive for Staphylococcus
aureus ability to escape from innate and adaptive immune responses, one can consider it as …

Staphylococcus aureus Small-Colony Variants Are Adapted Phenotypes for Intracellular Persistence

L Tuchscherr, V Heitmann, M Hussain… - The Journal of …, 2010 - academic.oup.com
Background. Staphylococcus aureus is an important human pathogen of endovascular
diseases, which can take a chronic course with a high relapse rate despite antimicrobial …

Evolution of methicillin-resistant Staphylococcus aureus towards increasing resistance

B Strommenger, MD Bartels, K Kurt… - Journal of …, 2014 - academic.oup.com
Objectives To elucidate the evolutionary history of Staphylococcus aureus clonal complex
(CC) 8, which encompasses several globally distributed epidemic lineages, including …

Comparative proteome analysis reveals conserved and specific adaptation patterns of Staphylococcus aureus after internalization by different types of human non …

K Surmann, S Michalik, P Hildebrandt… - Frontiers in …, 2014 - frontiersin.org
Staphylococcus aureus is a human pathogen that can cause a wide range of diseases.
Although formerly regarded as extracellular pathogen, it has been shown that S. aureus can …

Staphylococcus aureus small colony variants: a challenge to microbiologists and clinicians

C von Eiff - International journal of antimicrobial agents, 2008 - Elsevier
The pathogen Staphylococcus aureus may use various strategies to resist antibiotic therapy.
One of these strategies is the formation of small colony variants (SCVs), a naturally …

Clonal differences in Staphylococcus aureus bacteraemia-associated mortality

M Recker, M Laabei, MS Toleman, S Reuter… - Nature …, 2017 - nature.com
The bacterium Staphylococcus aureus is a major human pathogen for which the emergence
of antibiotic resistance is a global public health concern. Infection severity, and in particular …

Molecular Epidemiology of Staphylococcus aureus Bacteremia: Association of Molecular Factors With the Source of Infection

D Pérez-Montarelo, E Viedma, N Larrosa… - Frontiers in …, 2018 - frontiersin.org
Staphylococcus aureus bacteremia (SAB) is associated with high morbidity and mortality,
which varies depending on the source of infection. Nevertheless, the global molecular …