Development and validation of a high-performance liquid chromatography tandem mass spectrometry assay for atorvastatin, ortho-hydroxy atorvastatin, and para …
WW Bullen, RA Miller, RN Hayes - Journal of the American Society for …, 1999 - Springer
A liquid chromatographic/mass spectrometric method to quantitate atorvastatin (AT) and its
active metabolites ortho-hydroxy (o-AT) and para-hydroxy (p-AT) atorvastatin in human, dog …
active metabolites ortho-hydroxy (o-AT) and para-hydroxy (p-AT) atorvastatin in human, dog …
Simultaneous quantification of atorvastatin and active metabolites in human plasma by liquid chromatography–tandem mass spectrometry using rosuvastatin as …
RVS Nirogi, VN Kandikere, M Shukla… - Biomedical …, 2006 - Wiley Online Library
A simple, sensitive, selective and rapid liquid chromatography–tandem mass spectrometry
(LC‐MS/MS) method was developed and validated for the quantification of atorvastatin and …
(LC‐MS/MS) method was developed and validated for the quantification of atorvastatin and …
[HTML][HTML] Simultaneous quantitation of atorvastatin and its two active metabolites in human plasma by liquid chromatography/(–) electrospray tandem mass …
P Partani, SM Verma, S Gurule, A Khuroo… - Journal of pharmaceutical …, 2014 - Elsevier
A sensitive, accurate and selective liquid chromatography–tandem mass spectrometry
method (LC–MS/MS) was developed and validated for the simultaneous quantitation of …
method (LC–MS/MS) was developed and validated for the simultaneous quantitation of …
Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high‐performance liquid chromatography with …
M Jemal, Z Ouyang, BC Chen… - Rapid communications in …, 1999 - Wiley Online Library
A method for simultaneous quantitation of both the acid and lactone forms of atorvastatin, a
new synthetic inhibitor of HMG‐CoA reductase that is being marketed for the treatment of …
new synthetic inhibitor of HMG‐CoA reductase that is being marketed for the treatment of …
Determination of atorvastatin and metabolites in human plasma with solid-phase extraction followed by LC–tandem MS
M Hermann, H Christensen, JLE Reubsaet - Analytical and bioanalytical …, 2005 - Springer
The aim of the present study was to develop a chromatographic method for the analysis of
atorvastatin, o-and p-hydroxyatorvastatin (acid and lactone forms) in human plasma after …
atorvastatin, o-and p-hydroxyatorvastatin (acid and lactone forms) in human plasma after …
Development and validation of a sensitive, simple, and rapid method for simultaneous quantitation of atorvastatin and its acid and lactone metabolites by liquid …
JS Macwan, IA Ionita, M Dostalek… - Analytical and bioanalytical …, 2011 - Springer
The aim of the proposed work was to develop and validate a simple and sensitive assay for
the analysis of atorvastatin (ATV) acid, ortho-and para-hydroxy-ATV, ATV lactone, and ortho …
the analysis of atorvastatin (ATV) acid, ortho-and para-hydroxy-ATV, ATV lactone, and ortho …
Validated HPLC–MS–MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma—pharmacokinetic study
V Bořek-Dohalský, J Huclova, B Barrett… - Analytical and …, 2006 - Springer
Cholesterol-reducing statin drugs are the most frequently prescribed agents for reducing
morbidity and mortality related to coronary heart disease. In this publication a validated …
morbidity and mortality related to coronary heart disease. In this publication a validated …
Determination of atorvastatin in human serum by reversed-phase high-performance liquid chromatography with UV detection
G Bahrami, B Mohammadi, S Mirzaeei… - Journal of Chromatography …, 2005 - Elsevier
A rapid and sensitive high-performance liquid chromatographic method was validated and
described for determination of atorvastatin in human serum. Following liquid–liquid …
described for determination of atorvastatin in human serum. Following liquid–liquid …
Microsample determination of lovastatin and its hydroxy acid metabolite in mouse and rat plasma by liquid chromatography/ionspray tandem mass spectrometry
Y Wu, J Zhao, J Henion, WA Korfmacher… - Journal of mass …, 1997 - Wiley Online Library
A sensitive and specific method was developed and validated to quantitate lovastatin and its
hydroxy acid in mouse and rat plasma. This method employs a solid‐phase extraction …
hydroxy acid in mouse and rat plasma. This method employs a solid‐phase extraction …
Liquid chromatographic determination of atorvastatin in bulk drug, tablets, and human plasma
TG Altuntas, N Erk - Journal of liquid chromatography & related …, 2004 - Taylor & Francis
A simple, specific, and accurate high performance liquid chromatographic (HPLC) method
for determination of atorvastatin in bulk drug, tablets, and human plasma have been …
for determination of atorvastatin in bulk drug, tablets, and human plasma have been …
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