Objective: To provide a quantitative meta-analysis of the antidepressant effects of sleep
deprivation to complement qualitative reviews addressing response rates. Data Sources …

The literature suggests that sleep deprivation can potentiate the effect of antidepressant
medication in depressed patients. However, the clinical efficacy of sleep deprivation has not …

Total sleep deprivation (TSD) exerts beneficial but only transient effects on mood in patients
with a major depressive disorder (MDD). Though~ 50 to 70% of depressed patients improve …

Sleep deprivation (SD) is a powerful antidepressant treatment that shows antidepressant
responses within hours in 40–60% of depressed patients. In more than 80% of responders …

Is sleep deprivation useful in the treatment of depression? - Abstract - Europe PMC Sign in |
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Objective To systematically review evidence on the efficacy and safety of sleep deprivation
(SD) as a treatment option for patients with unipolar or bipolar depression. Methods A …

Sleep deprivation, alone or in combination with pharmacological treatment and as part of a
chronotherapy package, is of potential use for people with major depressive episodes …

Background: There are clinical as well as experimental indications that–contrary to what is
generally assumed—late partial sleep deprivation (LPSD) is not as effective as total sleep …

Objective: The authors' goal was to test the hypothesis that the antidepressant effect of total
sleep deprivation can be maintained by initially avoiding sleep during a supposedly “critical” …

Total sleep deprivation (TSD) exerts beneficial but transient effects on mood in
approximately 60% of patients with a major depressive disorder. The positive effects of a …