Hypoxia promotes luteal cell death in bovine corpus luteum

R Nishimura, J Komiyama, Y Tasaki… - Biology of …, 2008 - academic.oup.com
Low oxygen caused by a decreasing blood supply is known to induce various responses of
cells, including apoptosis. The present study was conducted to examine whether low …

Apoptosis, autophagic cell death, and necroptosis: different types of programmed cell death in bovine corpus luteum regression

T Hojo, DJ Skarzynski, K Okuda - Journal of Reproduction and …, 2022 - jstage.jst.go.jp
In mammals, the corpus luteum (CL) is a transient organ that secretes progesterone (P4). In
the absence of pregnancy, the CL undergoes regression (luteolysis), which is a crucial …

Regulatory changes of apoptotic factors in the bovine corpus luteum after induced luteolysis

H Kliem, B Berisha, HHD Meyer… - Molecular …, 2009 - Wiley Online Library
The corpus luteum (CL) offers the opportunity to study not only proliferative, but also
regressive processes. During luteolysis of the CL a sudden death of luteal and endothelial …

Reactive oxygen species up-regulates cyclooxygenase-2, p53, and Bax mRNA expression in bovine luteal cells

T Nakamura, K Sakamoto - Biochemical and Biophysical Research …, 2001 - Elsevier
Reactive oxygen species (ROS) are well-established modulators of luteal cell apoptosis in
the estrous cycle. The objective of this study was to clarify the molecular mechanisms of …

Potential regulators of physiological cell death in the corpus luteum

BR Rueda, DL Hamernik, PB Hoyer, JL Tilly - Cell Death in Reproductive …, 1997 - Springer
The corpus luteum (CL) is formed within the mammalian ovary from the remaining follicular
tissue following ovulation of the dominant follicle (s). The primary function of the CL is to …

Expression of genes associated with apoptosis in the porcine corpus luteum during the oestrous cycle

LM Zorrilla, MA D'Annibale, SE Swing… - … in Domestic Animals, 2013 - Wiley Online Library
Contents The corpus luteum (CL) of the pig lacks luteolytic sensitivity (LS) to prostaglandin
(PG) F‐2α until after day 12 of the oestrous cycle, but the mechanisms underlying this …

The effects of luteinizing hormone as a suppression factor for apoptosis in bovine luteal cells in vitro

A Bowolaksono, M Fauzi, AM Sundari… - … in Domestic Animals, 2021 - Wiley Online Library
The fate of the corpus luteum, a transient endocrine gland formed and degraded during an
oestrous cycle, is decided by various physiological factors, such as luteinizing hormone …

Species-related differences in the mechanism of apoptosis during structural luteolysis

N Sugino, K Okuda - Journal of Reproduction and Development, 2007 - jstage.jst.go.jp
Luteolysis is defined as the loss of function and subsequent involution of the luteal structure.
The luteolytic process is usually subdivided, whereby the decline in progesterone is …

[PDF][PDF] Early pregnancy modulates survival and apoptosis pathways in the corpus luteum in sheep

JH Lee, SK Banu, JA McCracken, JA Arosh - Reproduction, 2016 - researchgate.net
The corpus luteum (CL) is a transient endocrine gland. Functional and structural demise of
the CL allows a new estrous cycle. On the other hand, survival of CL and its secretion of …

Expression of superoxide dismutase, catalase and glutathione peroxidase in the bovine corpus luteum: evidence supporting a role for oxidative stress in luteolysis

BR Rueda, KI Tilly, TR Hansen, PB Hoyer, JL Tilly - Endocrine, 1995 - Springer
Apoptosis, a type of physiological or active cell death, has been implicated as a mechanism
underlying regression of the corpus luteum (CL) in the rat, bovine, rabbit and ovine ovary …