Combinatorial perspective on the gene expression circuits established by the CPEB-family of RNA binding proteins

B Duran Arqué - 2020 - diposit.ub.edu
[eng] The complex changes that take place in the mature Xenopus oocyte and early embryo
are orchestrated in the absence of transcription. Until zygotic transcription starts, after the …

[HTML][HTML] Global analysis of CPEBs reveals sequential and non-redundant functions in mitotic cell cycle

V Giangarra, A Igea, CL Castellazzi, FA Bava… - PLoS …, 2015 - journals.plos.org
CPEB (Cytoplasmic Polyadenylation Element Binding) proteins are a family of four RNA-
binding proteins that regulate the translation of maternal mRNAs controlling meiotic cell …

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins

T Afroz, L Skrisovska, E Belloc… - Genes & …, 2014 - genesdev.cshlp.org
Cytoplasmic changes in polyA tail length is a key mechanism of translational control and is
implicated in germline development, synaptic plasticity, cellular proliferation, senescence …

CPEB2, CPEB3 and CPEB4 are coordinately regulated by miRNAs recognizing conserved binding sites in paralog positions of their 3′-UTRs

M Morgan, A Iaconcig, AF Muro - Nucleic acids research, 2010 - academic.oup.com
The cytoplasmic polyadenylation element binding-protein (CPEB) is an RNA-binding protein
that participates in translational control. CPEB2, CPEB3 and CPEB4 are paralog proteins …

Meiosis requires a translational positive loop where CPEB1 ensues its replacement by CPEB4

A Igea, R Méndez - The EMBO journal, 2010 - embopress.org
Meiotic progression is driven by the sequential translational activation of maternal
messenger RNAs stored in the cytoplasm. This activation is mainly induced by the …

[HTML][HTML] Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulation

B Duran-Arqué, M Cañete, CL Castellazzi, A Bartomeu… - Genome Biology, 2022 - Springer
Background Vertebrate CPEB proteins bind mRNAs at cytoplasmic polyadenylation
elements (CPEs) in their 3′ UTRs, leading to cytoplasmic changes in their poly (A) tail …

Specificity of RNA binding by CPEB: requirement for RNA recognition motifs and a novel zinc finger

LE Hake, R Mendez, JD Richter - Molecular and cellular biology, 1998 - Am Soc Microbiol
ABSTRACT CPEB is an RNA binding protein that interacts with the maturation-type
cytoplasmic polyadenylation element (CPE)(consensus UUUUUAU) to promote …

The expression of CPEB proteins is sequentially regulated during zebrafish oogenesis and embryogenesis

ML O'Connell, WC Cavallo Jr… - Molecular Reproduction …, 2014 - Wiley Online Library
In many species, there is little transcription in the mature oocyte, and zygotic transcription
does not begin immediately after fertilization. In zebrafish, zygotic transcription is not initiated …

[HTML][HTML] CPEB3 Maintains Developmental Competence of the Oocyte

L Lamacova, D Jansova, Z Jiang, M Dvoran… - Cells, 2024 - mdpi.com
Mammalian oocyte development depends on the temporally controlled translation of
maternal transcripts, particularly in the coordination of meiotic and early embryonic …

Translational regulation of the cell cycle: when, where, how and why?

I Kronja, TL Orr-Weaver - Philosophical Transactions of …, 2011 - royalsocietypublishing.org
Translational regulation contributes to the control of archetypal and specialized cell cycles,
such as the meiotic and early embryonic cycles. Late meiosis and early embryogenesis …