A Key Regulator of the Glycolytic and Gluconeogenic Central Metabolic Pathways in Sinorhizobium meliloti

GC diCenzo, Z Muhammed, M Østerås, SAP O'Brien… - Genetics, 2017 - academic.oup.com
The order Rhizobiales contains numerous agriculturally, biotechnologically, and medically
important bacteria, including the rhizobia, and the genera Agrobacterium, Brucella, and …

Increased pyruvate orthophosphate dikinase activity results in an alternative gluconeogenic pathway in Rhizobium (Sinorhizobium) meliloti

østerås Magne, BT Driscoll, TM Finan - Microbiology, 1997 - microbiologyresearch.org
The formation of phosphoenolpyruvate (PEP) is a major step in the gluconeogenic pathway
in which tricarboxylic acid (TCA) cycle intermediates are converted to hexose sugars. In …

Genetic Analysis of Mutations Affecting pckA Regulation in Rhizobium (Sinorhizobium) meliloti

M Østerås, SAP O'Brien, TM Finan - Genetics, 1997 - academic.oup.com
The enzyme phosphoenolpyruvate carboxykinase (Pck) catalyzes the first step in the
gluconeogenic pathway in most organisms. We are examining the genetic regulation of the …

Physiology, genetics, and biochemistry of carbon metabolism in the alphaproteobacterium Sinorhizobium meliloti

BA Geddes, IJ Oresnik - Canadian journal of microbiology, 2014 - cdnsciencepub.com
A large proportion of genes within a genome encode proteins that play a role in metabolism.
The Alphaproteobacteria are a ubiquitous group of bacteria that play a major role in a …

Site-directed mutagenesis and DNA sequence of pckA of Rhizobium NGR234, encoding phosphoenolpyruvate carboxykinase: gluconeogenesis and host …

M Østerås, TM Finan, J Stanley - Molecular and General Genetics MGG, 1991 - Springer
We have cloned and sequenced the pckA gene of Rhizobium sp. NGR234, a broad host-
range strain. The gene encodes phosphoenolpyruvate carboxykinase (PEPCK), a key …

Molecular and expression analysis of the Rhizobium meliloti phosphoenolpyruvate carboxykinase (pckA) gene

M Osterås, BT Driscoll, TM Finan - Journal of bacteriology, 1995 - Am Soc Microbiol
The pckA gene of Rhizobium meliloti, encoding phosphoenolpyruvate carboxykinase, was
isolated from a genomic cosmid library by complementation of the succinate growth …

The global nitrogen regulator GlnR is a direct transcriptional repressor of the key gluconeogenic gene pckA in actinomycetes

X Liu, X Wang, Z Shao, J Dang, W Wang… - Journal of …, 2024 - Am Soc Microbiol
In most actinomycetes, GlnR governs both nitrogen and non-nitrogen metabolisms (eg,
carbon, phosphate, and secondary metabolisms). Although GlnR has been recognized as a …

Gluconeogenesis in Rhizobium leguminosarum MNF3841

IA McKay, AR Glenn, MJ Dilworth - Microbiology, 1985 - microbiologyresearch.org
Gluconeogenesis in Rhizobium leguminosarum MNF3841 takes place via the derepressible
enzymes phosphoenolpyruvate carboxykinase (PEPCK) and fructose bisphosphate …

Transcriptome Analysis of Polyhydroxybutyrate Cycle Mutants Reveals Discrete Loci Connecting Nitrogen Utilization and Carbon Storage in Sinorhizobium meliloti

M D'Alessio, R Nordeste, AC Doxey, TC Charles - Msystems, 2017 - Am Soc Microbiol
Polyhydroxybutyrate (PHB) and glycogen polymers are produced by bacteria as carbon
storage compounds under unbalanced growth conditions. To gain insights into the …

HPrK Regulates Succinate-Mediated Catabolite Repression in the Gram-Negative Symbiont Sinorhizobium meliloti

CA Pinedo, DJ Gage - Journal of bacteriology, 2009 - Am Soc Microbiol
The HPrK kinase/phosphatase is a common component of the phosphotransferase system
(PTS) of gram-positive bacteria and regulates catabolite repression through …