Meiosis Leads to Pervasive Copy-Number Variation and Distorted Inheritance of Accessory Chromosomes of the Wheat Pathogen Zymoseptoria tritici

S Fouché, C Plissonneau… - Genome biology and …, 2018 - academic.oup.com
Meiosis is one of the most conserved molecular processes in eukaryotes. The fidelity of
pairing and segregation of homologous chromosomes has a major impact on the proper …

Breakage-fusion-bridge cycles and large insertions contribute to the rapid evolution of accessory chromosomes in a fungal pathogen

D Croll, M Zala, BA McDonald - PLoS Genetics, 2013 - journals.plos.org
Chromosomal rearrangements are a major driver of eukaryotic genome evolution, affecting
speciation, pathogenicity and cancer progression. Changes in chromosome structure are …

Repeat-Induced Point Mutation and Gene Conversion Coinciding with Heterochromatin Shape the Genome of a Plant-Pathogenic Fungus

J Komluski, M Habig, EH Stukenbrock - Mbio, 2023 - Am Soc Microbiol
Meiosis is associated with genetic changes in the genome—via recombination, gene
conversion, and mutations. The occurrence of gene conversion and mutations during …

[HTML][HTML] Next-generation re-sequencing as a tool for rapid bioinformatic screening of presence and absence of genes and accessory chromosomes across isolates of …

MC McDonald, AH Williams, A Milgate… - Fungal Genetics and …, 2015 - Elsevier
The wheat pathogen Zymoseptoria tritici possesses a large number of accessory
chromosomes that may be present or absent in its genome. The genome of the reference …

Forward Genetics Approach Reveals Host Genotype-Dependent Importance of Accessory Chromosomes in the Fungal Wheat Pathogen Zymoseptoria tritici

M Habig, J Quade, EH Stukenbrock - MBio, 2017 - Am Soc Microbiol
The fungal wheat pathogen Zymoseptoria tritici possesses a large complement of accessory
chromosomes showing presence/absence polymorphism among isolates. These …

Interspecific gene exchange introduces high genetic variability in crop pathogen

A Feurtey, DM Stevens, W Stephan… - Genome Biology and …, 2019 - academic.oup.com
Genome analyses have revealed a profound role of hybridization and introgression in the
evolution of many eukaryote lineages, including fungi. The impact of recurrent introgression …

Expression Profiling of the Wheat Pathogen Zymoseptoria tritici Reveals Genomic Patterns of Transcription and Host-Specific Regulatory Programs

R Kellner, A Bhattacharyya, S Poppe… - Genome biology and …, 2014 - academic.oup.com
Host specialization by pathogens requires a repertoire of virulence factors as well as fine-
tuned regulation of gene expression. The fungal wheat pathogen Zymoseptoria tritici …

Extraordinary genome instability and widespread chromosome rearrangements during vegetative growth

M Möller, M Habig, M Freitag, EH Stukenbrock - Genetics, 2018 - academic.oup.com
The ability to rapidly adapt to changing environments is crucial for the success of pathogens
infecting plants and animals. In some eukaryotic pathogens, rapid evolution can be …

The impact of recombination hotspots on genome evolution of a fungal plant pathogen

D Croll, MH Lendenmann, E Stewart, BA McDonald - Genetics, 2015 - academic.oup.com
Recombination has an impact on genome evolution by maintaining chromosomal integrity,
affecting the efficacy of selection, and increasing genetic variability in populations …

Pangenome analyses of the wheat pathogen Zymoseptoria tritici reveal the structural basis of a highly plastic eukaryotic genome

C Plissonneau, FE Hartmann, D Croll - BMC biology, 2018 - Springer
Background Structural variation contributes substantially to polymorphism within species.
Chromosomal rearrangements that impact genes can lead to functional variation among …