Mechanisms underpinning sympathoexcitation in hypoxia
LL Simpson, M Stembridge… - The Journal of …, 2024 - Wiley Online Library
Sympathoexcitation is a hallmark of hypoxic exposure, occurring acutely, as well as
persisting in acclimatised lowland populations and with generational exposure in highland …
persisting in acclimatised lowland populations and with generational exposure in highland …
A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies
LL Simpson, CD Steinback… - Experimental …, 2021 - Wiley Online Library
New Findings What is the topic of the review? Sympathoexcitation and sympathetic control
of blood pressure at high altitude. What advances does it highlight? Sustained …
of blood pressure at high altitude. What advances does it highlight? Sustained …
Sympathetic neural overactivity in healthy humans after prolonged exposure to hypobaric hypoxia
J Hansen, M Sander - The Journal of physiology, 2003 - Wiley Online Library
Acute exposure to hypoxia causes chemoreflex activation of the sympathetic nervous
system. During acclimatization to high altitude hypoxia, arterial oxygen content recovers, but …
system. During acclimatization to high altitude hypoxia, arterial oxygen content recovers, but …
Carotid chemoreceptor control of muscle sympathetic nerve activity in hypobaric hypoxia
New Findings What is the central question of this study? High‐altitude hypoxia increases
muscle sympathetic nerve activity (MSNA), but whether intravenous infusion of dopamine, to …
muscle sympathetic nerve activity (MSNA), but whether intravenous infusion of dopamine, to …
Sustained sympathetic activity in altitude acclimatizing lowlanders and high‐altitude natives
C Lundby, J Calbet, G Van Hall… - … journal of medicine & …, 2018 - Wiley Online Library
Combined results from different independent studies suggest that acclimatization to high
altitude induces a slowly developing sympathetic activation, even at levels of hypoxia that …
altitude induces a slowly developing sympathetic activation, even at levels of hypoxia that …
Does the sympathetic nervous system adapt to chronic altitude exposure?
M Sander - Hypoxia: Translation in Progress, 2016 - Springer
During continued exposure to hypobaric hypoxia in acclimatizing lowlanders increasing
norepinephrine levels indirectly indicate sympathoexcitation, and in a few subjects serial …
norepinephrine levels indirectly indicate sympathoexcitation, and in a few subjects serial …
Influence of sympathoexcitation at high altitude on cerebrovascular function and ventilatory control in humans
PN Ainslie, SJE Lucas, JL Fan… - Journal of Applied …, 2012 - journals.physiology.org
We sought to determine the influence of sympathoexcitation on dynamic cerebral
autoregulation (CA), cerebrovascular reactivity, and ventilatory control in humans at high …
autoregulation (CA), cerebrovascular reactivity, and ventilatory control in humans at high …
Baroreflex control of sympathetic vasomotor activity and resting arterial pressure at high altitude: insight from Lowlanders and Sherpa
LL Simpson, SA Busch, SJ Oliver… - The Journal of …, 2019 - Wiley Online Library
Key points Hypoxia, a potent activator of the sympathetic nervous system, is known to
increase muscle sympathetic nerve activity (MSNA) to the peripheral vasculature of native …
increase muscle sympathetic nerve activity (MSNA) to the peripheral vasculature of native …
Duration at high altitude influences the onset of arrhythmogenesis during apnea
LF Berthelsen, S Van Diepen, AR Steele… - European Journal of …, 2022 - Springer
Purpose Autonomic control of the heart is balanced by sympathetic and parasympathetic
inputs. Excitation of both sympathetic and parasympathetic systems occurs concurrently …
inputs. Excitation of both sympathetic and parasympathetic systems occurs concurrently …
Baroreflex and chemoreflex interaction in high-altitude exposure: possible role on exercise performance
P Alvarez-Araos, S Jiménez, C Salazar-Ardiles… - Frontiers in …, 2024 - frontiersin.org
The hypoxic chemoreflex and the arterial baroreflex are implicated in the ventilatory
response to exercise. It is well known that long-term exercise training increases …
response to exercise. It is well known that long-term exercise training increases …