• Infections involving cysts of patients with autosomal-dominant polycystic kidney disease
(PCKD) are often refractory to therapy possibly because of poor penetration of antibiotics …

Methods Cyst fluid was obtained from six patients with PCKD (Table 1). The patients ranged
in age from 45 to 63 years (mean, 53.6 years). All patients had typical features of PCKD, with …

Trimethoprim-sulfamethoxazole in cyst fluid from autosomal dominant polycystic kidneys.
Cyst infection in patients with autosomal-dominant polycystic kidney disease (ADPKD) is …

Cyst infection in autosomal dominant polycystic kidney disease (ADPKD) poses a difficult
diagnostic and therapeutic problem. We describe a serious indolent cyst infection due to …

Upper urinary tract (renal) infections have been reported to be frequent and difficult to treat
in patients with autosomal dominant polycystic kidney disease. This study examined renal …

This study examines the causes for the therapeutic failure of trimethoprim-sulfamethoxazole
in a patient with infected cysts caused by a sensitive strain of Escherichia coli. We …

We determined the concentrations of clindamycin and gentamicin in fluid aspirated from 16
cysts of a surgically excised polycystic kidney. The patient had received both drugs …

We previously predicted that highly lipid soluble antibiotics would be very effective in the
treatment of infected cysts in autosomal dominant polycystic kidney disease (ADPKD). This …

Cyst infection is a frequent and serious complication of autosomal dominant polycystic
kidney disease (ADPKD) that is often difficult to treat and can be fatal. However, much is still …

Renal infection is a common occurrence in autosomal dominant polycystic kidney disease
(ADPKD) and often leads to serious complications, including perinephric abscess …