Although tetanus and diphtheria have become rare in developed countries, pertussis is still
endemic in some developed countries. These are vaccine-preventable diseases and …

Pertussis is an important cause of morbidity and mortality, and its incidence has been
increasing in adolescents and adults over the past two decades. Waning immunity in …

BACKGROUND: Increasing incidence of pertussis in adolescents and adults has stimulated
the development of safe and immunogenic acellular pertussis vaccines for booster …

Acellular pertussis vaccines combined with diphtheria and tetanus toxoids have proven to
be well tolerated, immunogenic and effective in reducing pertussis disease in adolescents …

Pertussis causes substantial morbidity among adolescents and adults, as well as other
persons in contact with affected individuals. In the context of widespread childhood …

Background: Due to the resurgence of pertussis, many countries have revised the pertussis
immunization schedules and recommended booster doses of pertussis component vaccine …

Background: The epidemiology of pertussis is changing, with a clear increase in the number
of cases diagnosed in adolescents and adults. This development has spurred studies and …

Transmission of pertussis among adults is being increasingly recognized. About 1 or 2 in
1,000 adolescents and adults develop pertussis each year,⩾ 12% of persons with acute …

Background. Pertussis is among the most poorly controlled bacterial vaccine-preventable
diseases in the United States. In 2006, a tetanus, reduced-dose diphtheria, and acellular …

Availability of combined tetanus-diphtheria-acellular pertussis (Tdap) vaccines for adults
offers a new pertussis prevention strategy for the US. Successful uptake of Tdap vaccine will …