The maintenance of meiotic prophase arrest in fully grown vertebrate oocytes depends on
the activity of a Gs G-protein that activates adenylyl cyclase and elevates cAMP, and in the …

In mammalian oocytes, the maintenance of meiotic prophase I arrest prior to the surge of LH
that stimulates meiotic maturation depends on a high level of cAMP within the oocyte. In …

The arrest of meiotic prophase in mouse oocytes within antral follicles requires the G protein
Gs and an orphan member of the G protein–coupled receptor family, GPR3. To determine …

Oocytes are held in meiotic arrest in prophase I until ovulation, when gonadotropins trigger a
subpopulation of oocytes to resume meiosis in a process termed “maturation.” Meiotic arrest …

The maintenance of meiotic prophase arrest in mouse oocytes within fully grown follicles,
prior to the surge of luteinizing hormone (LH) that triggers meiotic resumption, depends on a …

In mammalian and amphibian oocytes, the meiotic arrest at the G2/M transition is dependent
on cAMP regulation. Because genetic inactivation of a phosphodiesterase expressed in …

In nearly every vertebrate species, elevated intracellular cAMP maintains oocytes in
prophase I of meiosis. Prior to ovulation, gonadotropins trigger various intra-ovarian …

Vertebrate oocytes are naturally arrested at prophase of meiosis I for sustained periods of
time before resuming meiosis in a process called oocyte maturation that prepares the egg …

After becoming competent for resuming meiosis, fully developed mammalian oocytes are
maintained arrested in prophase I until ovulation is triggered by the luteotropin surge …

The signaling pathway by which luteinizing hormone (LH) acts on the somatic cells of
vertebrate ovarian follicles to stimulate meiotic resumption in the oocyte requires a decrease …