Triple inhaler versus dual bronchodilator therapy in COPD: real-world effectiveness on mortality

S Suissa, S Dell'Aniello, P Ernst - COPD: Journal of Chronic …, 2022 - Taylor & Francis
Randomized trials of triple therapy including an inhaled corticosteroid (ICS) for chronic
obstructive pulmonary disease (COPD) reported remarkable benefits on mortality compared …

[HTML][HTML] Impact of switching from triple therapy to dual bronchodilation in COPD: the DACCORD 'real world'study

CF Vogelmeier, H Worth, R Buhl, CP Criée… - Respiratory …, 2022 - Springer
Introduction Chronic obstructive pulmonary disease (COPD) guidelines recommend
reserving triple therapy of inhaled corticosteroid (ICS), long-acting β2-agonist (LABA) and …

Single-inhaler triple versus dual bronchodilator therapy in COPD: real-world comparative effectiveness and safety

S Suissa, S Dell'Aniello, P Ernst - International Journal of Chronic …, 2022 - Taylor & Francis
Purpose Randomized trials report that single-inhaler triple therapy is more effective than
dual bronchodilators at reducing exacerbations in patients with chronic obstructive …

[HTML][HTML] Comparative effectiveness of triple therapy versus dual bronchodilation in COPD

J Voorham, M Corradi, A Papi… - ERJ Open …, 2019 - Eur Respiratory Soc
This real-world study compared the effectiveness of triple therapy (TT; long-acting
muscarinic antagonists (LAMAs)/long-acting inhaled β-agonists (LABAs)/inhaled …

Triple therapy in COPD: what we know and what we don't

PMA Calverley, H Magnussen… - COPD: Journal of …, 2017 - Taylor & Francis
Triple inhaled therapy for chronic obstructive pulmonary disease (COPD) consists of an
inhaled corticosteroid (ICS), a long-acting β2-agonist (LABA) and a long-acting muscarinic …

Triple therapy trials in COPD: a precision medicine opportunity

S Suissa, A Ariel - European Respiratory Journal, 2018 - Eur Respiratory Soc
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy document for the
treatment of chronic obstructive pulmonary disease (COPD) suggests that, after …

Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis

M Cazzola, P Rogliani, L Calzetta… - European Respiratory …, 2018 - Eur Respiratory Soc
We performed a meta-analysis to compare the impact of triple combination therapy with
inhaled corticosteroids (ICS), long-acting β2-agonists (LABAs) and long-acting muscarinic …

[HTML][HTML] Prescribing pathways to triple therapy: a multi-country, retrospective observational study of adult patients with chronic obstructive pulmonary disease

JK Quint, C O'Leary, A Venerus, M Myland… - Pulmonary therapy, 2020 - Springer
Introduction Maintenance treatment strategies in COPD recommend inhaled corticosteroid
(ICS)+ long-acting muscarinic antagonist (LAMA)+ long-acting β 2-agonist (LABA) triple …

Triple versus dual inhaler therapy in moderate‐to‐severe COPD: A systematic review and meta‐analysis of randomized controlled trials

Y Zayed, M Barbarawi, B Kheiri… - The clinical …, 2019 - Wiley Online Library
Introduction Treatment of chronic obstructive pulmonary disease (COPD) is evolving
specially with triple inhaler therapy. Objectives To perform a meta‐analysis to ascertain the …

[HTML][HTML] Trends and characteristics of global initiative for chronic obstructive lung disease guidelines-discordant prescribing of triple therapy among patients with …

SP Bhatt, C Blauer-Peterson, EK Buysman… - … Diseases: Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Triple therapy (long-acting muscarinic antagonist [LAMA] plus long-acting
beta2-agonist [LABA] plus inhaled corticosteroid [ICS]) is recommended by the Global …