[HTML][HTML] Role of tear film biomarkers in the diagnosis and management of dry eye disease

PY Fong, KC Shih, PY Lam, TCY Chan… - Taiwan journal of …, 2019 - journals.lww.com
In recent years, there has been increasing scientific interest in the use of tear film biomarkers
in the diagnosis and management of dry eye disease (DED), owing to their potential …

[HTML][HTML] Tear biomarkers in dry eye disease: Progress in the last decade

NR Kumar, M Praveen, R Narasimhan… - Indian journal of …, 2023 - journals.lww.com
Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …

Severity, therapeutic, and activity tear biomarkers in dry eye disease: An analysis from a phase III clinical trial

J Pinto-Fraga, A Enríquez-de-Salamanca, M Calonge… - The ocular …, 2018 - Elsevier
Purpose To evaluate the effect of 0.1%-fluorometholone (FML) on tear inflammatory
molecule levels after 22-days treatment in dry eye disease (DED) patients exposed to an …

[PDF][PDF] Tear biomarkers in dry eye disease

A Chiva - Eur. Ophthalmic Rev, 2019 - touchophthalmology.com
The diagnosis of dry eye disease (the early stages in particular) is important, but difficult, due
to the lack of gold standards and poor correlation between tear biochemical changes and …

[HTML][HTML] Evaluations of tear protein markers in dry eye disease: repeatability of measurement and correlation with disease

JF Huang, Y Zhang, KD Rittenhouse… - … & visual science, 2012 - jov.arvojournals.org
Methods.: In this prospective study, based on the ocular surface disease index (OSDI) and
corneal staining (CS), 95 DED patients (OSDI≥ 13) with increasing CS were enrolled into 3 …

[HTML][HTML] Correlations between tear cytokines, chemokines, and soluble receptors and clinical severity of dry eye disease

KS Na, JW Mok, JY Kim, CR Rho… - … ophthalmology & visual …, 2012 - iovs.arvojournals.org
Purpose.: To determine cytokine and chemokine concentrations in the tears of patients with
dry eye disease (DED) and analyze the possible relationships with the clinical severity of …

Association of tear cytokine concentrations with symptoms and signs of dry eye disease: Baseline data from the Dry Eye Assessment and Management (DREAM) …

NS Roy, Y Wei, GS Ying, MG Maguire… - Current eye …, 2023 - Taylor & Francis
Purpose To describe tear concentrations of IL-1β, Il-6, IL-8, IL-10, IL-17A, IFNγ and TNFα in
tears, collected by microcapillaries, and their correlation with symptoms and signs in …

[HTML][HTML] Dry eye and biomarkers: present and future

N Deschamps, C Baudouin - Current Ophthalmology Reports, 2013 - Springer
Dry eye disease (DED) is a complex disorder of the ocular surface. Due to the lack of
consistency between clinical signs and symptoms and poor clinical indicators of …

[HTML][HTML] New approaches for diagnosis of dry eye disease

AM Elhusseiny, AA Khalil, RH El Sheikh… - International journal …, 2019 - ncbi.nlm.nih.gov
We reviewed the literature for different diagnostic approaches for dry eye disease (DED)
including the most recent advances, contradictions and promising diagnostic tools and …

[HTML][HTML] Practical issues concerning tear protein assays in dry eye

S D'Souza, L Tong - Eye and Vision, 2014 - Springer
Dry eye is a common clinical condition diagnosed by cumulative evidence of symptoms and
signs. Many new treatments in dry eye are either expensive, invasive, have potential for side …