On the Role of CD8+ T Cells in Determining Recovery Time from Influenza Virus Infection
Myriad experiments have identified an important role for CD8+ T cell response mechanisms
in determining recovery from influenza A virus infection. Animal models of influenza infection …
in determining recovery from influenza A virus infection. Animal models of influenza infection …
Mathematical model reveals the role of memory CD8 T cell populations in recall responses to influenza
The current influenza vaccine provides narrow protection against the strains included in the
vaccine, and needs to be reformulated every few years in response to the constantly …
vaccine, and needs to be reformulated every few years in response to the constantly …
Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity
MA Myers, AP Smith, LC Lane, DJ Moquin, R Aogo… - Elife, 2021 - elifesciences.org
Influenza viruses cause a significant amount of morbidity and mortality. Understanding host
immune control efficacy and how different factors influence lung injury and disease severity …
immune control efficacy and how different factors influence lung injury and disease severity …
Simulation and prediction of the adaptive immune response to influenza A virus infection
HY Lee, DJ Topham, SY Park, J Hollenbaugh… - Journal of …, 2009 - Am Soc Microbiol
The cellular immune response to primary influenza virus infection is complex, involving
multiple cell types and anatomical compartments, and is difficult to measure directly. Here …
multiple cell types and anatomical compartments, and is difficult to measure directly. Here …
Innate immunity and the inter-exposure interval determine the dynamics of secondary influenza virus infection and explain observed viral hierarchies
Influenza is an infectious disease that primarily attacks the respiratory system. Innate
immunity provides both a very early defense to influenza virus invasion and an effective …
immunity provides both a very early defense to influenza virus invasion and an effective …
Assessing mathematical models of influenza infections using features of the immune response
HM Dobrovolny, MB Reddy, MA Kamal, CR Rayner… - PloS one, 2013 - journals.plos.org
The role of the host immune response in determining the severity and duration of an
influenza infection is still unclear. In order to identify severity factors and more accurately …
influenza infection is still unclear. In order to identify severity factors and more accurately …
Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus
Seasonal and pandemic influenza A virus (IAV) continues to be a public health threat.
However, we lack a detailed and quantitative understanding of the immune response …
However, we lack a detailed and quantitative understanding of the immune response …
Modeling within-host dynamics of influenza virus infection including immune responses
KA Pawelek, GT Huynh, M Quinlivan… - PLoS computational …, 2012 - journals.plos.org
Influenza virus infection remains a public health problem worldwide. The mechanisms
underlying viral control during an uncomplicated influenza virus infection are not fully …
underlying viral control during an uncomplicated influenza virus infection are not fully …
Model of influenza A virus infection: dynamics of viral antagonism and innate immune response
M Fribourg, B Hartmann, M Schmolke… - Journal of theoretical …, 2014 - Elsevier
Viral antagonism of host responses is an essential component of virus pathogenicity. The
study of the interplay between immune response and viral antagonism is challenging due to …
study of the interplay between immune response and viral antagonism is challenging due to …
Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host
The cellular adaptive immune response plays a key role in resolving influenza infection.
Experiments where individuals are successively infected with different strains within a short …
Experiments where individuals are successively infected with different strains within a short …