The hypothalamus contains the highest diversity of neurons in the brain. Many of these
neurons can co-release neurotransmitters and neuropeptides in a use-dependent manner …

The hypothalamus is an evolutionarily conserved endocrine interface that, among other
roles, links central homeostatic control to adaptive bodily responses by releasing hormones …

The hypothalamic arcuate–median eminence complex (Arc-ME) controls energy balance,
fertility and growth through molecularly distinct cell types, many of which remain unknown …

The hypothalamus plays a key role in coordinating fundamental body functions. Despite
recent progress in single-cell technologies, a unified catalog and molecular characterization …

Abstract Pro-opiomelanocortin (POMC)-expressing neurons in the arcuate nucleus of the
hypothalamus represent key regulators of metabolic homeostasis. Electrophysiological and …

The ventromedial hypothalamus (VMH) is a distinct morphological nucleus involved in
feeding, fear, thermoregulation, and sexual activity. It is essentially unknown how VMH …

The hypothalamus is one of the most complex brain structures involved in homeostatic
regulation. Defining cell composition and identifying cell-type-specific transcriptional …

Hypothalamic neuron circuits regulating energy balance are highly plastic and develop in
response to nutrient and hormonal cues. To identify processes that might be susceptible to …

INTRODUCTION A mechanistic understanding of brain function requires the identification of
distinct cell types in the brain at a molecular, spatial, and functional level. The preoptic …

A wealth of specialized neuroendocrine command systems intercalated within the
hypothalamus control the most fundamental physiological needs in vertebrates …