Sex-dependent alterations in social behaviour and cortical synaptic activity coincide at different ages in a model of Alzheimer's disease
Besides memory deficits, Alzheimer's disease (AD) patients suffer from neuropsychiatric
symptoms, including alterations in social interactions, which are subject of a growing …
symptoms, including alterations in social interactions, which are subject of a growing …
Age-related changes in social behaviours in the 5xFAD mouse model of Alzheimer's disease
F Kosel, PT Munoz, JR Yang, AA Wong… - Behavioural Brain …, 2019 - Elsevier
In addition to memory impairments, patients with Alzheimer's disease (AD) exhibit a number
of behavioural and psychological symptoms that can affect social interactions over the …
of behavioural and psychological symptoms that can affect social interactions over the …
Impact of social relationships on Alzheimer's memory impairment: mechanistic studies
YH Hsiao, CH Chang, PW Gean - Journal of biomedical science, 2018 - Springer
Alzheimer's disease (AD) is characterized by progressive memory and neuronal loss
culminating in cognitive impairment that not only affects a person's living ability but also …
culminating in cognitive impairment that not only affects a person's living ability but also …
Sex‐specific accelerated decay in time/activity‐dependent plasticity and associative memory in an animal model of Alzheimer's disease
S Navakkode, JR Gaunt, MV Pavon, VA Bansal… - Aging …, 2021 - Wiley Online Library
Clinical studies have shown that female brains are more predisposed to neurodegenerative
diseases such as Alzheimer's disease (AD), but the cellular and molecular mechanisms …
diseases such as Alzheimer's disease (AD), but the cellular and molecular mechanisms …
Sex differences in behavior and molecular pathology in the 5XFAD model
A Sil, A Erfani, N Lamb, R Copland… - Journal of …, 2022 - content.iospress.com
Background: The prevalence of Alzheimer's disease (AD) is greater in women compared to
men, but the reasons for this remain unknown. This sex difference has been widely …
men, but the reasons for this remain unknown. This sex difference has been widely …
Limited impact of social isolation on Alzheimer-like symptoms in a triple transgenic mouse model.
S Pietropaolo, Y Sun, R Li, C Brana… - Behavioral …, 2009 - psycnet.apa.org
Gene-environment interactions are known to play a major role in the ethiopathology of
several neuropsychiatric disorders, including Alzheimer's disease (AD). The present study …
several neuropsychiatric disorders, including Alzheimer's disease (AD). The present study …
Early development of social deficits in APP and APP-PS1 mice
S Pietropaolo, P Delage, F Lebreton, WE Crusio… - Neurobiology of …, 2012 - Elsevier
Mimicking relevant behavioral features of the human pathology is one of the most important
challenges for animal models of neurological disorders including Alzheimer disease (AD) …
challenges for animal models of neurological disorders including Alzheimer disease (AD) …
Sex differences in patterns of associative memory-related activation in individuals at risk of Alzheimer's disease
N Corriveau-Lecavalier, L Décarie-Labbé, S Mellah… - Neurobiology of …, 2022 - Elsevier
The risk of developing Alzheimer's disease dementia is higher in females compared to
males and is greater in individuals with subjective cognitive decline and mild cognitive …
males and is greater in individuals with subjective cognitive decline and mild cognitive …
[HTML][HTML] Long-term social isolation stress exacerbates sex-specific neurodegeneration markers in a natural model of Alzheimer's disease
Social interactions have a significant impact on health in humans and animal models. Social
isolation initiates a cascade of stress-related physiological disorders and stands as a …
isolation initiates a cascade of stress-related physiological disorders and stands as a …
Sexual dimorphism in the 3xTg-AD mouse model and its impact on pre-clinical research
JL Dennison, NR Ricciardi, I Lohse… - Journal of …, 2021 - content.iospress.com
Female sex is a leading risk factor for developing Alzheimer's disease (AD). Sexual
dimorphism in AD is gaining attention as clinical data show that women are not only more …
dimorphism in AD is gaining attention as clinical data show that women are not only more …