Trehalose acts as a uridine 5′‐diphosphoglucose‐competitive inhibitor of trehalose 6‐phosphate synthase in Corynebacterium glutamicum

S Oide, M Inui - The FEBS Journal, 2017 - Wiley Online Library
Trehalose is a compatible solute widely distributed in nature. The most prevalent pathway
for its synthesis starts from condensation of glucose 6‐phosphate (Glc6P) and uridine 5 …

Overproduction of trehalose: heterologous expression of Escherichia coli trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase in …

L Padilla, R Krämer, G Stephanopoulos… - Applied and …, 2004 - Am Soc Microbiol
Trehalose is a disaccharide with potential applications in the biotechnology and food
industries. We propose a method for industrial production of trehalose, based on improved …

[PDF][PDF] Trehalosesynthese in Corynebacterium glutamicum

A Wolf - 2002 - kups.ub.uni-koeln.de
The non-reducing disaccharide trehalose is ubiquitously distributed in nature and commonly
found among prokaryotic and eukaryotic organisms where it is employed as a general stress …

Three pathways for trehalose metabolism in Corynebacterium glutamicum ATCC13032 and their significance in response to osmotic stress

A Wolf, R Krämer, S Morbach - Molecular microbiology, 2003 - Wiley Online Library
Genome scanning of Corynebacterium glutamicum ATCC13032 revealed the presence of
five different genes encoding enzymes belonging to three putative trehalose biosynthesis …

Genetic dissection of trehalose biosynthesis in Corynebacterium glutamicum: inactivation of trehalose production leads to impaired growth and an altered cell wall …

M Tzvetkov, C Klopprogge, O Zelder… - Microbiology, 2003 - microbiologyresearch.org
The analysis of the available Corynebacterium genome sequence data led to the proposal
of the presence of all three known pathways for trehalose biosynthesis in bacteria, ie …

Heterologous expression of Escherichia coli ppsA (phosphoenolpyruvate synthetase) and galU (UDP-glucose pyrophosphorylase) genes in Corynebacterium …

L Padilla, E Agosin - Metabolic Engineering, 2005 - Elsevier
Trehalose is a disaccharide with a wide range of applications in the food industry. We
recently proposed a strategy for trehalose production based on a Corynebacterium …

Metabolic Engineering of Corynebacterium glutamicum for Trehalose Overproduction: Role of the TreYZ Trehalose Biosynthetic Pathway

J Carpinelli, R Krämer, E Agosin - Applied and environmental …, 2006 - Am Soc Microbiol
Trehalose has many potential applications in biotechnology and the food industry due to its
protective effect against environmental stress. Our work explores microbiological production …

Impact of Heterologous Expression of Escherichia coli UDP-Glucose Pyrophosphorylase on Trehalose and Glycogen Synthesis in Corynebacterium glutamicum

L Padilla, S Morbach, R Krämer… - Applied and …, 2004 - Am Soc Microbiol
Trehalose is a disaccharide with a wide range of applications in the food industry. We
recently proposed a strategy for trehalose production based on improved strains of the gram …

Biochemical and genetic characterization of the pathways for trehalose metabolism in Propionibacterium freudenreichii, and their role in stress response

FS Cardoso, RF Castro, N Borges… - Microbiology, 2007 - microbiologyresearch.org
Propionibacterium freudenreichii accumulates high levels of trehalose, especially in
response to stress. The pathways for trehalose metabolism were characterized, and their …

Trends in bacterial trehalose metabolism and significant nodes of metabolic pathway in the direction of trehalose accumulation

R Ruhal, R Kataria, B Choudhury - Microbial Biotechnology, 2013 - Wiley Online Library
The current knowledge of trehalose biosynthesis under stress conditions is incomplete and
needs further research. Since trehalose finds industrial and pharmaceutical applications …