Lipodystrophies are an immense group of genetic or acquired metabolic disorders that are
characterized by varying degrees of body fat loss and in some instances localized …

Lipodystrophies, heterogeneous acquired or inherited disorders characterized by the
selective loss of adipose tissue, predispose affected patients to insulin resistance and its …

Purpose of review This article focuses on recent progress in understanding the genetics of
lipodystrophy syndromes, the pathophysiology of severe metabolic abnormalities caused by …

Background The lipodystrophy syndromes are genetic or acquired disorders characterized
by selective loss of adipose tissue that may involve the entire body (generalized) or only …

Lipodystrophies are a heterogeneous group of physiological changes characterized by a
selective loss of fatty tissue. Here, no fat cells are present, either through lack of …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

HIV-associated lipodystrophy, arising as a result of long-term therapy with antiretroviral
medications, is a complex syndrome characterized by changes in regional fat mass …

Lipodystrophy constitutes a spectrum of diseases characterized by a generalized or partial
absence of adipose tissue. Underscoring the role of healthy fat in maintenance of metabolic …

The introduction of highly active antiretroviral therapy (HAART) including nucleoside reverse
transcriptase inhibitors (NRTI) and protease inhibitors (PI) has dramatically improved the …

Since the introduction of HIV-1 protease inhibitors as components of antiretroviral drug
combination regimens, the clinical course of HIV disease and opportunistic infections has …