[HTML][HTML] Preplanned safety analysis of the JFMC37-0801 trial: a randomized phase III study of six months versus twelve months of capecitabine as adjuvant …

T Suto, M Ishiguro, C Hamada, K Kunieda… - International journal of …, 2017 - Springer
Background Six months of adjuvant chemotherapy is regarded as the standard of care for
patients with stage III colon cancer. However, whether longer treatment can improve …

Phase III trial of 24 weeks vs. 48 weeks capecitabine adjuvant chemotherapy for patients with stage III colon cancer: final results of JFMC37-0801

S Yamaguchi, K Kunieda, T Sato… - Annals of …, 2016 - annalsofoncology.org
Background JFMC37-0801 study was planned to offer superiority of 48 weeks treatment of
capecitabine adjuvant chemotherapy to 24 weeks conventional treatment with respect to the …

[HTML][HTML] Phase III randomised trial comparing 6 vs. 12-month of capecitabine as adjuvant chemotherapy for patients with stage III colon cancer: final results of the …

N Tomita, K Kunieda, A Maeda, C Hamada… - British Journal of …, 2019 - nature.com
Background Up to 6-months oxaliplatin-containing regimen is now widely accepted as a
standard adjuvant chemotherapy for stage III colorectal cancer (CRC). However, oral …

5-year overall survival update from the X-ACT trial of capecitabine vs 5-FU/LV as adjuvant treatment for stage III colon cancer

C Twelves, W Scheithauer, J McKendrick… - Eur. J. Cancer …, 2007 - academia.edu
Background: Intravenous bolus 5-fluorouracil plus leucovorin (5-FU/LV) is the standard
adjuvant treatment for colon cancer. The oral fluoropyrimidine capecitabine is an …

Early safety findings from a phase III trial of capecitabine plus oxaliplatin (XELOX) vs. bolus 5-FU/LV as adjuvant therapy for patients (pts) with stage III colon cancer

HJ Schmoll, J Tabernero, M Nowacki… - Journal of Clinical …, 2005 - ascopubs.org
3523 Background: In a large phase III study (X-ACT) in stage III colon cancer, adjuvant
capecitabine was at least equivalent to bolus 5-FU/LV for disease-free survival (DFS). In the …

Review of completed and ongoing trials of capecitabine-based adjuvant therapy in patients with early-stage colon cancer.

J Cassidy, N Scotto, E Diaz-Rubio - Journal of Clinical Oncology, 2011 - ascopubs.org
495 Background: Capecitabine is an established alternative to 5-FU in gastrointestinal
cancers. In metastatic colorectal cancer, capecitabine is non-inferior to 5-FU and …

Capecitabine versus S-1 as adjuvant chemotherapy for patients with stage III colorectal cancer (JCOG0910): an open-label, non-inferiority, randomised, phase 3 …

T Hamaguchi, Y Shimada, J Mizusawa… - The lancet …, 2018 - thelancet.com
Background Adjuvant chemotherapy with oral fluoropyrimidine alone after D3/D2 lymph
node dissection improves disease-free survival and overall survival in patients with stage III …

Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: a planned safety analysis in 1,864 patients

HJ Schmoll, T Cartwright, J Tabernero… - Journal of Clinical …, 2006 - ascopubs.org
Purpose To report the results of a planned safety analysis from a phase III trial comparing
capecitabine plus oxaliplatin (XELOX) with bolus fluorouracil/leucovorin (FU/LV) as adjuvant …

[HTML][HTML] Capecitabine as adjuvant treatment for stage III colon cancer

C Twelves, A Wong, MP Nowacki, M Abt… - … England Journal of …, 2005 - Mass Medical Soc
Background Intravenous bolus fluorouracil plus leucovorin is the standard adjuvant
treatment for colon cancer. The oral fluoropyrimidine capecitabine is an established …

Redefining adjuvant chemotherapy in patients with stage III colon cancer: X-ACT trial

H Glen, J Cassidy - Expert review of anticancer therapy, 2008 - Taylor & Francis
The current standard adjuvant chemotherapy for suitable patients with stage III colon cancer
is the combination of oxaliplatin and 5-fluorouracil plus folinic acid (5-FU/LV). However, until …