[HTML][HTML] α-Mangostin mediated pharmacological modulation of hepatic carbohydrate metabolism in diabetes induced Wistar rat

V Kumar, PC Bhatt, G Kaithwas, M Rashid… - Beni-suef university …, 2016 - Elsevier
Garcinia mangostana L.(Fruit) has been commonly used as folklore drug in the treatment of
various types of diseases. The present experiment was designed to evaluate the potential …

Alpha-mangostin improves cardiac hypertrophy and fibrosis and associated biochemical parameters in high-fat/high-glucose diet and low-dose streptozotocin …

V Soetikno, A Murwantara, P Andini… - Journal of …, 2020 - Taylor & Francis
Purpose The aim of present study was to analyze the effect of alpha-mangostin on cardiac
hypertrophy and fibrosis and biochemical parameters in high-fat/high-glucose diet and low …

Hypoglycaemic activity of ethanolic extract of Garcinia mangostana Linn. in normoglycaemic and streptozotocin-induced diabetic rats

M Taher, TMFS Tg Zakaria, D Susanti… - BMC complementary and …, 2016 - Springer
Abstract Background Various parts of Garcinia mangostana Linn., including its pericarp,
have been traditionally used to treat a variety of ailments. In an attempt to establish its …

[HTML][HTML] Mangosteen xanthone γ-mangostin exerts lowering blood glucose effect with potentiating insulin sensitivity through the mediation of AMPK/PPARγ

SP Chen, SR Lin, TH Chen, HS Ng, HS Yim… - Biomedicine & …, 2021 - Elsevier
Diabetes mellitus (DM) is concomitant with significant morbidity and mortality and its
prevalence is accumulative in worldwide. The conventional antidiabetic agents are known to …

[PDF][PDF] Renal protective effects of gamma-mangostin in streptozotocin-induced diabetic mice

SA Husen, ANMA Salamun, S Hayaza… - Indian Journal of …, 2020 - researchgate.net
This study was aimed to investigate the ability of gamma-mangostin to reduce plasma blood
urea nitrogen (BUN) and creatinine and ameliorates the impaired renal proximal tubular …

Hepatoprotective effect of gamma-mangostin for amelioration of impaired liver structure and function in streptozotocin-induced diabetic mice

SA Husen, D Winarni, ANM Ansori… - … Series: Earth and …, 2018 - iopscience.iop.org
The aim of this study was to investigate whether gamma-mangostin could reduce fasting
blood glucose, cholesterol, SGOT, SGPT, and also ameliorate damaged hepatocytes in …

Alpha-mangostin improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage

D Lee, YM Kim, K Jung, YW Chin, KS Kang - International Journal of …, 2018 - mdpi.com
Alpha (α)-mangostin, a yellow crystalline powder with a xanthone core structure, is isolated
from mangosteen (Garcinia mangostana), which is a tropical fruit of great nutritional value …

The effect of juice mangosteen rind (Garcinia mangostana L.) to blood sugar levels and histological of pancreatic rats with the induction of streptozotocin

M Kurniawati, C Mahdi - The Journal of Pure and Applied …, 2014 - search.proquest.com
Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by high blood sugar
levels as a result of insufficiency of insulin function. Xanton a bioactive compound in the …

Antidiabetic activity of mango peel extract and mangiferin in alloxan-induced diabetic rats

J Mistry, M Biswas, S Sarkar, S Ghosh - Future Journal of Pharmaceutical …, 2023 - Springer
Background In diabetic animals, there is a significant increase in plasma glucose, serum
total cholesterol, triglyceride, and low-density lipoprotein levels, and decreased body weight …

The metabolic and molecular mechanisms of α‑mangostin in cardiometabolic disorders

OD John, AT Mushunje… - International …, 2022 - spandidos-publications.com
Abstract α‑mangostin is a xanthone predominantly encountered in Garcinia mangostana.
Extensive research has been carried out concerning the effects of this compound on various …