Clinical implications of fetuin-A

P Jirak, L Stechemesser, E Moré, M Franzen… - Advances in clinical …, 2019 - Elsevier
Fetuin-A, also termed alpha2-Heremans-Schmid glycoprotein, is a 46 kDa hepatocyte
derived protein (hepatokine) and serves multifaceted functions.(i) It acts as systemic inhibitor …

[HTML][HTML] Limited Proteolysis of Human α2-HS Glycoprotein/Fetuin: VIDENCE THAT A CHYMOTRYPTIC ACTIVITY CAN RELEASE THE CONNECTING PEPTIDE

P Nawratil, S Lenzen, J Kellermann, H Haupt… - Journal of Biological …, 1996 - ASBMB
α 2-HS glycoprotein is a major protein of human plasma whose function is still obscure. A
proteolytically processed form of α 2-HS glycoprotein lacking a segment of 40 amino acid …

Serum fetuin‐A in metabolic and inflammatory pathways in patients with myocardial infarction

K Vörös, L Gráf Jr, Z Prohászka, L Gráf… - European journal of …, 2011 - Wiley Online Library
Eur J Clin Invest 2011; 41 (7): 703–709 Abstract Background Although multifunctional
glycoprotein α2HS‐glycoprotein/human fetuin‐A (AHSG) is involved in atherosclerosis, it is …

Changes in the expression of N-and O-glycopeptides in patients with colorectal cancer and hepatocellular carcinoma quantified by full-MS scan FT-ICR and multiple …

P Darebna, P Novak, R Kucera, O Topolcan… - Journal of …, 2017 - Elsevier
Alternations in the glycosylation of proteins have been described in connection with several
cancers, including hepatocellular carcinoma (HCC) and colorectal cancer. Analytical tools …

Association of AHSG gene polymorphisms with serum Fetuin-A levels in individuals with cardiovascular calcification in west of Iran

E Mohammadi-Noori, N Salehi, H Mozafari… - Molecular biology …, 2020 - Springer
Fetuin-A (AHSG) is a multifunctional secretory protein and acts as an ectopic valve and
artery calcification inhibitor. We assessed the correlation between serum levels of Fetuin-A …

An Enzymatic Deglycosylation Scheme Enabling Identification of Core Fucosylated N-Glycans and O-Glycosylation Site Mapping of Human Plasma Proteins

P Hägglund, R Matthiesen, F Elortza… - Journal of proteome …, 2007 - ACS Publications
Global proteome analysis of protein glycosylation is a major challenge due to the inherent
heterogeneous and diverse nature of this post-translational modification. It is therefore …

LC‐MS3 quantification of O‐glycopeptides in human serum

M Sanda, P Pompach, J Benicky, R Goldman - Electrophoresis, 2013 - Wiley Online Library
Quantitative analysis of site‐specific glycosylation of proteins is a challenging part of
glycoproteomic research. Multiple enrichment steps are typically required in the analytical …

Assessment of lectin and HILIC based enrichment protocols for characterization of serum glycoproteins by mass spectrometry

CD Calvano, CG Zambonin, ON Jensen - Journal of proteomics, 2008 - Elsevier
Protein glycosylation is a common post-translational modification that is involved in many
biological processes, including cell adhesion, protein–protein and receptor-ligand …

Serum fetuin‐A concentrations are elevated in subjects with impaired glucose tolerance and newly diagnosed type 2 diabetes

HY Ou, YC Yang, HT Wu, JS Wu, FH Lu… - Clinical …, 2011 - Wiley Online Library
Objective Hepatic steatosis is associated with an increased risk of diabetes. Although the
levels of serum fetuin‐A, a liver‐derived glycoprotein that impairs insulin signalling, are …

[HTML][HTML] Fetuin-A protein distribution in mature inflamed and ischemic brain tissue

MC Heinen, A Babler, J Weis, J Elsas, K Nolte, M Kipp… - PLoS …, 2018 - journals.plos.org
Background The liver-derived plasma protein fetuin-A is strongly expressed during fetal life,
hence its name. Fetuin-A protein is normally present in most fetal organs and tissues …