Despite continuous advances in hyperglycemia treatments, a precise control through
monitoring of glucose and glycated hemoglobin remains in most diabetic patients as the …

Changes in N-linked glycosylation are known to occur during the development of cancer.
For example, we have previously reported changes in N-linked glycosylation that occur with …

Human lung cancer is a major cause of cancer mortality worldwide. Advances in
pathophysiologic understanding and novel biomarkers for diagnosis and treatment are …

The majority of human proteins are post-translationally modified by covalent addition of one
or more complex oligosaccharides (glycans). Alterations in glycosylation processing are …

Clinical proteomics has been defined as 'the application of proteomic analysis with the aim
of solving a specific clinical problem within the context of a clinical study'[1]. As many of the …

Glycosylation is an important PTM and is critical for the manufacture and efficacy of
therapeutic glycoproteins. Glycan significantly influences the biological properties of human …

Mass spectrometry–based glycoproteomics has gone through some incredible
developments over the last few years. Technological advances in glycopeptide enrichment …

Recent analytical advancements allow for large-scale glycomics and glycan-biomarker
research with N-glycans released from complex protein mixtures of eg plasma with a wide …

Fetuin-A is a pro-inflammatory protein expressed by hepatocytes. Its course in morbidly
obese patients with NAFLD (non-alcoholic fatty liver disease) following weight loss by BAS …

Over half of all proteins are glycosylated, and alterations in glycosylation have been
observed in numerous physiological and pathological processes. Attached glycans …