Biliary atresia leads to cirrhosis in the vast majority of patients and constitutes the first cause
of paediatric liver transplantation. Animal models allow us to understand the molecular basis …

Background/purpose Biliary atresia and other liver biliary obstructions are relevant
conditions in pediatric surgery due to their progression to biliary cirrhosis and indication for …

Background The murine model of biliary atresia (BA) is used for examining the pathogenesis
of BA. The aim of the study was description of the morphological features and illustrating the …

Background Biliary atresia (BA) is a cholestatic liver disease of children that progresses to
hepatic fibrosis. BA is the main indication of pediatric liver transplantation (LTx) …

Background/Aims: Biliary atresia and paucity of intrahepatic bile ducts are the main causes
of neonatal cholestasis leading to hepatic fibrosis. Fibrotic evolution is slow in paucity of bile …

BA is the most important disease requiring liver transplantation in children. Common BDL in
rats is a classic experimental model to study biliary obstruction. The response of the …

Background Extrahepatic biliary atresia results from a progressive destruction of the bile
ducts by an inflammatory fibrosing process which leads ultimately to cirrhosis of biliary type …

BACKGROUND/PURPOSE: The mechanisms of increased collagen production and liver
parenchyma fibrosis are poorly understood. These phenomena are observed mainly in …

Surgical bile flow restoration in extrahepatic biliary atresia (EHBA) does not prevent the
development of ongoing hepatic fibrosis and cirrhosis. Portal connective matrix was studied …

Secondary biliary cirrhosis in the rat can be induced by bile duct ligation; the aim of the
present study was to investigate whether susceptibility to this injury depends on …