Psoriasis and systemic inflammatory disorders

T Tashiro, Y Sawada - International journal of molecular sciences, 2022 - mdpi.com
Psoriasis is a representative inflammatory skin disease occupied by large surface
involvement. As inflammatory cells and cytokines can systemically circulate in various …

Psoriasis: pathogenesis, comorbidities, and therapy updated

N Kanda - International journal of molecular sciences, 2021 - mdpi.com
Psoriasis is a chronic inflammatory skin disease characterized by IL-17-dominant abnormal
innate and acquired immunity, and the hyperproliferation and aberrant differentiation of …

The risk of systemic diseases in those with psoriasis and psoriatic arthritis: from mechanisms to clinic

YR Woo, CJ Park, H Kang, JE Kim - International Journal of Molecular …, 2020 - mdpi.com
Psoriasis and psoriatic arthritis (PsA) have been recently considered as chronic systemic
inflammatory disorders. Over the past decades, enormous evidence indicates that patients …

Pathogenesis, multi-omics research, and clinical treatment of psoriasis

J Yu, Q Zhao, X Wang, H Zhou, J Hu, L Gu, Y Hu… - Journal of …, 2022 - Elsevier
Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Advances in understanding the immunological pathways in psoriasis

SR Georgescu, M Tampa, C Caruntu, MI Sarbu… - International journal of …, 2019 - mdpi.com
Psoriasis vulgaris is a chronic, immune-mediated, inflammatory, polygenic skin disorder
affecting approximately 2% of the population. It has a great impact on quality of life; patients …

Molecular mechanisms and management of a cutaneous inflammatory disorder: psoriasis

YR Woo, DH Cho, HJ Park - International Journal of Molecular Sciences, 2017 - mdpi.com
Psoriasis is a complex chronic inflammatory cutaneous disorder. To date, robust molecular
mechanisms of psoriasis have been reported. Among diverse aberrant immunopathogenetic …

Current concepts of psoriasis immunopathogenesis

M Vičić, M Kaštelan, I Brajac, V Sotošek… - International Journal of …, 2021 - mdpi.com
Psoriasis is a recurrent, chronic, immune-mediated, systemic inflammatory disease of the
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …

The cytokine mediated molecular pathophysiology of psoriasis and its clinical implications

R Singh, S Koppu, PO Perche, SR Feldman - International journal of …, 2021 - mdpi.com
Psoriasis is the result of uncontrolled keratinocyte proliferation, and its pathogenesis
involves the dysregulation of the immune system. The interplay among cytokines released …

Insights into interplay of immunopathophysiological events and molecular mechanistic cascades in psoriasis and its associated comorbidities

AK Srivastava, TC Yadav, HK Khera, P Mishra… - Journal of …, 2021 - Elsevier
Psoriasis is an inflammatory skin disease with complex pathogenesis and multiple
etiological factors. Besides the essential role of autoreactive T cells and constellation of …

Therapeutic development based on the immunopathogenic mechanisms of psoriasis

JC Tseng, YC Chang, CM Huang, LC Hsu, TH Chuang - Pharmaceutics, 2021 - mdpi.com
Psoriasis, a complex inflammatory autoimmune skin disorder that affects 2–3% of the global
population, is thought to be genetically predetermined and induced by environmental and …