The multifunctional, anti-Alzheimer drug, ladostigil (TV3326)[(N-propargyl-(3R) aminoindan-
5yl)-ethyl methyl carbamate] combines the neuroprotective effects of the anti-Parkinson …

Abstract Emodin (EM; 1, 3, 8-trihydroxy-6-methylanthracene-9, 10-dione; C 15 H 10 O 5) is
an anthraquinone and exerts cytoprotective effects, as observed in both in vitro and in vivo …

The oxidative phosphorylation (OXPHOS) system located in the mitochondria is the main
source of adenosine triphosphate (ATP) in mammals. The mitochondria are also the main …

Alzheimer's disease (AD) is the most common neurodegenerative disorder, responsible for>
50% of all dementia cases. Sodium azide (NaN3) inhibits cytochrome oxidase by irreversibly …

Oxidative stress plays an important role in Parkinson's disease and other neurodegenerative
disorders. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea L., has …

Background Parkinson's disease (PD) is a progressive neurodegenerative disorder of the
central nervous system. Although the causes of PD pathogenesis remain incomplete, some …

Abstract Bergenia ciliata (Haw) Sternb. possess immunomodulatory, anti-inflammatory,
antioxidant, anti-urolithiatic, wound healing, anti-malarial, anti-diabetic and anti-cancer …

Oxidative stress plays a critical role in the pathogenesis of various neurodegenerative
diseases. Increasing evidence suggests the association of mitochondrial abnormalities with …

The total GSH depletion observed in the substantia nigra (SN) appears to be responsible for
subsequent oxidative stress (OS), mitochondrial dysfunction, and dopaminergic cell loss in …

Parkinson's disease (PD) is the second-most common neurodegenerative disease, and the
development and progression of PD is characterized by oxidative stress (OS). This study …