Mitochondrial dysfunction, oxidative stress and apoptotic induction in microglial BV-2 cells treated with sodium arsenate

W Kharroubi, SH Ahmed, T Nury, P Andreoletti… - Journal of …, 2017 - Elsevier
The treatment of microglial BV-2 cells with sodium arsenate (As (V): 0.1–400 μmol/L—48 hr)
induces a dose-dependent response. The neurotoxic effects of high concentrations of As …

Fasudil mesylate protects PC12 cells from oxidative stress injury via the Bax-mediated pathway

Q Li, D Liu, X Huang, L Guo - Cellular and molecular neurobiology, 2011 - Springer
We previously reported that fasudil mesylate (FM) improves neurological deficit and
neuronal damage in rats with ischemia following middle cerebral artery occlusion and …

Effects of sulforaphane on brain mitochondria: mechanistic view and future directions

FR Jardim, FJS de Almeida, MD Luckachaki… - Journal of Zhejiang …, 2020 - Springer
The organosulfur compound sulforaphane (SFN; C 6 H 11 NOS 2) is a potent cytoprotective
agent promoting antioxidant, anti-inflammatory, antiglycative, and antimicrobial effects in in …

Kaurane diterpenes as mitochondrial alterations preventive agents under experimental oxidative stress conditions

E González-Burgos, AI Duarte, ME Carretero… - Pharmaceutical …, 2016 - Taylor & Francis
Context: Foliol, linearol, and sidol are the most common diterpenes found in Sideritis L.
spp.(Lamiaceae) with a wide range of demonstrated properties including anti-inflammatory …

Resveratrol prevents ammonia-induced mitochondrial dysfunction and cellular redox imbalance in C6 astroglial cells

LD Bobermin, DO Souza, CA Gonçalves… - Nutritional …, 2018 - Taylor & Francis
Background: Resveratrol is a polyphenolic compound that presents several protective
effects in the central nervous system, including gliotoxicity associated to hyperammonemia …

Silymarin versus Silibinin: Differential Antioxidant and Neuroprotective Effects against H2O2-induced Oxidative Stress in PC12 Cells

HH Jiang, FS Yan, L Shen… - Natural product …, 2016 - journals.sagepub.com
The present study assessed comparatively the antioxidant activities of silymarin and its
major active component silibinin and their neuroprotective effects against hydrogen …

Protective effects of active compounds from salviae miltiorrhizae Radix against glutamate-induced HT-22 hippocampal neuronal cell death

HM Phung, S Lee, KS Kang - Processes, 2020 - mdpi.com
Oxidative stress is considered one of the factors that cause dysfunction and damage of
neurons, causing diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease …

[HTML][HTML] Apigenin ameliorates oxidative stress-induced neuronal apoptosis in SH-SY5Y cells

YJ Kim, EJ Cho, AY Lee, WT Seo - 2021 - mbl.or.kr
The overproduction of reactive nitrogen species (RNS) and reactive oxygen species (ROS)
causes oxidative damage to neuronal cells, leading to the progression of neurodegenerative …

Neuroprotective Effect of Salvia sahendica is Mediated by Restoration of Mitochondrial Function and Inhibition of Endoplasmic Reticulum Stress

F Shaerzadeh, SZ Alamdary, MA Esmaeili… - Neurochemical …, 2011 - Springer
Herein, we investigated the protective effect of Salvia sahendica against H 2 O 2-induced
cell death in rat pheochromocytoma (PC12) cells. Our data show that S. sahendica blocks …

Saikosaponin-D Reduces H2O2-Induced PC12 Cell Apoptosis by Removing ROS and Blocking MAPK-Dependent Oxidative Damage

X Lin, S Wu, Q Wang, Y Shi, G Liu, J Zhi… - Cellular and Molecular …, 2016 - Springer
Neuronal oxidative stress (OS) injury has been proven to be associated with many
neurodegenerative diseases, and thus, antioxidation treatment is an effective method for …