Evaluating the efficacy and tolerance of atorvastatin in hyperlipidemia in general practice (SWITCH Study)

G Noseda, R Darioli, U Keller, R Mordasini… - Schweizerische …, 2000 - europepmc.org
Elevated levels of serum lipids and lipoproteins are known to play a major role in the
development of atherosclerosis and subsequent coronary heart disease (CHD). In controlled …

Comparison of the efficacy and safety of atorvastatin with simvastatin in patients with primary hypercholesterolemia

DM Black - Atherosclerosis, 1997 - elibrary.ru
Atorvastatin and simvastatin are both effective in lowering LDL-C and TC in hyperlipidemic
patients. The usual starting dose for both agents is 10 mg once daily, although for …

Efficacy and safety of atorvastatin and pravastatin in patients with hypercholesterolemia

G Assmann, D Hüwel, KM Schussman… - European Journal of …, 1999 - Elsevier
This 1-year, double-blind, active-controlled, multicenter study compared the efficacy and
safety of atorvastatin to pravastatin and evaluated their ability to achieve target low-density …

Efficacy and safety of a new cholesterol synthesis inhibitor, atorvastatin, in comparison with simvastatin and pravastatin, in subjects with hypercholesterolemia

BHR Wolffenbuttel, G Mahla, D Muller, A Pentrup… - The Netherlands journal …, 1998 - Elsevier
Background: High levels of total and LDL-cholesterol are associated with an increased risk
of atherosclerotic vascular disease. Lowering of serum cholesterol levels by pharmacologic …

A randomized, double-blind, placebo-controlled, 8-week study to evaluate the efficacy and safety of once daily atorvastatin (10 mg) in patients with elevated LDL …

KY Wang, CT Ting - Japanese heart journal, 2001 - jstage.jst.go.jp
Lowering of serum cholesterol levels by pharmacologic intervention with statins reduces the
incidence of cardiovascular events in subjects with and without atherosclerotic …

Two-year comparison of safety and efficacy of atorvastatin and lovastatin

RG Bakker-Arkema, L Shurzinske, M Davidson… - Atherosclerosis, 1997 - elibrary.ru
In this 2-year study, 787 patients with hypercholesterolemia received either atorvastatin 10
mg to 80 mg/day (623 patients) or lovastatin 20 mg to 80 mg/day (164 patients). Patients …

Efficacy and safety of atorvastatin compared to pravastatin in patients with hypercholesterolemia

S Bertolini, GB Bon, LM Campbell, M Farnier, J Langan… - Atherosclerosis, 1997 - Elsevier
Plasma cholesterol and other lipoproteins play a significant role in the development of
atherosclerosis and subsequent coronary heart disease (CHD). This 1 year study was …

The short-term effects of atorvastatin on lipid levels in patients with hyperlipidemia

H Schrott, M Davila, DM Black - Atherosclerosis, 1997 - elibrary.ru
Hyperlipidemia is a major risk factor for coronary heart disease (CHD). It is now well
established that reducing increased LDL-C levels can significantly reduce the risk of CHD …

Atorvastatin therapy under clinical practice conditions-which LDL-C levels are achieved in patients at very high cardiovascular risk?

U Laufs, C Jannowitz, D Pittrow - … Medizinische Wochenschrift (1946 …, 2017 - europepmc.org
Current information on the utilisation of atorvastatin under clinical practice conditions is
limited. The cross sectional study DISCOVER documented in the period from June until …

A brief review paper of the efficacy and safety of atorvastatin in early clinical trials

RG Bakker-Arkema, J Best, R Fayyad, TM Heinonen… - Atherosclerosis, 1997 - Elsevier
Preclinical and clinical data on atorvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A
(HMG-CoA) reductase inhibitor, indicate that it has superior activity in treating a variety of …