Prostate cancer is the most commonly diagnosed cancer among men in the United States as
well as most Western countries. A significant proportion of men report having a positive …

Prostate cancer has been known to run in families for about 40 years and epidemiological
studies have demonstrated an increased risk to close relatives of cases. This risk rises …

Importance Prostate cancer is the third leading cause of cancer-related death in men in the
United States. Although serious, most of these diagnoses are not terminal. Inherited risk for …

Prostate cancer is a significant public health problem. There are about 14000 cases per year
in England and Wales, and 10000 deaths [J]. In the USA, it is the most common malignancy …

BACKGROUND It seems unlikely that the large ethnic differences in prostate cancer risk can
be explained completely by ethnic differences in diet or other lifestyle characteristics …

Prostate cancer (PrCa) is the most common non-skin cancer diagnosed among males in
developed countries and the second leading cause of cancer mortality, yet little is known …

Prostate cancer rates vary substantially by race, ethnicity, and geography. These disparities
can be explained by variation in access to screening and treatment, variation in exposure to …

OBJECTIVE To identify published studies quantifying familial prostate cancer risks in
relatives of prostate cancer cases and, by meta‐analysis, obtain more precise estimates of …

Recent studies suggest that hereditary prostate cancer is a complex disease involving
multiple susceptibility genes and variable phenotypic expression. While conducting a …

Background: Familial prostate cancer risk estimates are inflated by clinically insignificant low-
risk cancer, diagnosed after prostate-specific antigen testing. We provide age-specific …