It has been suggested that baicalein, a flavonoid obtained from the Scutellaria root, exerts a
protective role on neurons against several neuronal insults. However, the protective …

Mitochondrial dysfunction has long been associated with neurodegenerative disease.
Therefore, mitochondrial protective agents represent a unique direction for the development …

Astrocytes play a key role in brain homeostasis, protecting neurons against neurotoxic
stimuli such as oxidative stress. Therefore, the neuroprotective therapeutics that enhance …

Astrocyte mitochondria play an important role for energy supply and neuronal survival in the
brain. Toxic and degenerative processes are largely associated with mitochondrial …

Abstract Carnosic acid (CA; C 20 H 28 O 4) is a phenolic diterpene found in rosemary
(Rosmarinus officinalis L.) and exhibits protective properties, eg, antioxidant, anti …

Mitochondrial dysfunctions have been implicated in the progression of Huntington's disease
(HD). To date, several free radical scavengers have been tested in experimental HD, but …

Excessive and sustained increases in oxidative stress and apoptosis have been implicated
in the pathogenesis of many diseases. In this study, we demonstrated that 4 …

Traumatic brain injury (TBI) is a major source of mortality and long‐term disability worldwide.
The mechanisms associated with TBI development are poorly understood, and little …

Abstract The kynurenines 3-hydroxyanthranilic acid (3-HANA) and its precursor 3-
hydroxykynurenine (3-HK) are metabolites derived from tryptophan degradation. 3-HK, has …

The progression of neurological diseases is mainly attributed to oxidative stress, apoptosis,
inflammation, and trauma, making them a primary public concern. Since no drugs can stop …