Cardiovascular disease is the most common cause of death in the United States and
worldwide. Most of this disease is preventable with improvement of lifestyle and medication …

Statins (HMG-CoA reductase inhibitors) are one of the most widely prescribed medications
in the world. However, their use in patients is often inappropriate because these medications …

The role of low-density lipoprotein cholesterol (LDL-C) in the pathophysiology of
atherosclerosis and coronary artery disease has been well documented. 1 The use of 3 …

In randomized trials and meta-analyses, statins decrease myocardial infarction, stroke,
vascular death, and total mortality. 1 The totality of evidence indicates no threshold below …

Controversy erupted last fall when new guidelines from the American Heart Association and
American College of Cardiology altered recommendations for cholesterol-lowering statin …

" Treatment of Patients with Lipid Disorders in the Primary Care Setting: New Treatment
Guidelines and Their Implications"'presents a thorough review of the lowering of lipid levels …

In women and men, cardiovascular disease is and will remain the leading avoidable cause
of premature death in the United States and is rapidly becoming so worldwide. 1 Although …

In this issue of The American Journal of Medicine, Hennekens et al 1 address many cogent
methodologic issues concerning whether there is a valid statistical association between …

Cardiovascular disease is the number one cause of morbidity and mortality in the United
States, and the prevalence of this disease has been increasing since 2015. 1 Poor patient …

Aggressive intervention to lower low-density lipoprotein cholesterol (LDL-C) with statin
therapy significantly reduces cardiovascular risk [1]. Target levels of LDL-C levels between …