Inhibition of c-Jun N-terminal kinase and nuclear factor κ B pathways mediates fisetin-exerted anti-inflammatory activity in lipopolysccharide-treated RAW264. 7 cells
SC Kim, SH Kang, SJ Jeong, SH Kim… - Immunopharmacology …, 2012 - Taylor & Francis
Although fisetin, a natural flavonoid, was known to inhibit proliferation, carcinogenesis and
inflammation, the underlying anti-inflammatory mechanism of fistein still remains unclear …
inflammation, the underlying anti-inflammatory mechanism of fistein still remains unclear …
[HTML][HTML] Fisetin suppresses macrophage-mediated inflammatory responses by blockade of Src and Syk
JH Kim, MY Kim, JH Kim, JY Cho - Biomolecules & therapeutics, 2015 - ncbi.nlm.nih.gov
Abstract Flavonoids, such as fisetin (3, 7, 3′, 4′-tetrahydroxyflavone), are plant secondary
metabolites. It has been reported that fisetin is able to perform numerous pharmacological …
metabolites. It has been reported that fisetin is able to perform numerous pharmacological …
Dihydrofisetin exerts its anti-inflammatory effects associated with suppressing ERK/p38 MAPK and Heme Oxygenase-1 activation in lipopolysaccharide-stimulated …
KK Li, SS Shen, X Deng, HT Shiu, WS Siu… - International …, 2018 - Elsevier
Dihydrofisetin is a flavanonol derived from some edible wild herbs and traditional Chinese
medicines. It has been found to possess many biological activities. However, the anti …
medicines. It has been found to possess many biological activities. However, the anti …
Fisetin inhibits the generation of inflammatory mediators in interleukin-1β–induced human lung epithelial cells by suppressing the NF-κB and ERK1/2 pathways
HL Peng, WC Huang, SC Cheng, CJ Liou - International …, 2018 - Elsevier
Fisetin, a flavone that can be isolated from fruits and vegetables, has anti-tumor and anti-
oxidative properties and ameliorates airway hyperresponsiveness in asthmatic mice. This …
oxidative properties and ameliorates airway hyperresponsiveness in asthmatic mice. This …
Fisetin Attenuates Lipopolysaccharide‐Induced Inflammatory Responses in Macrophage
Y Hada, HA Uchida, J Wada - BioMed research international, 2021 - Wiley Online Library
Several studies have reported the efficacy and safety of polyphenols in human health;
however, the verification of their efficacy remains insufficient. The aim of this study was to …
however, the verification of their efficacy remains insufficient. The aim of this study was to …
Anti-inflammatory activity of fisetin in human gingival fibroblasts treated with lipopolysaccharide
G Gutiérrez-Venegas… - Journal of Asian …, 2014 - Taylor & Francis
Fisetin is an anti-inflammatory flavonoid; however, its anti-inflammatory mechanism is not yet
understood. In this study, we evaluated the anti-inflammatory effect of fisetin and its …
understood. In this study, we evaluated the anti-inflammatory effect of fisetin and its …
Fisetin, a dietary flavonoid, ameliorates experimental colitis in mice: Relevance of NF-κB signaling
Fisetin, a dietary flavonoid, is commonly found in many fruits and vegetables. Although
studies indicate that fisetin has an anti-inflammatory property, little is known about its effects …
studies indicate that fisetin has an anti-inflammatory property, little is known about its effects …
[HTML][HTML] Fisetin inhibits lipopolysaccharide-induced inflammatory response by activating β-catenin, leading to a decrease in endotoxic shock
IMN Molagoda, JACC Jayasingha, YH Choi… - Scientific Reports, 2021 - nature.com
Fisetin is a naturally occurring flavonoid that possesses several pharmacological benefits
including anti-inflammatory activity. However, its precise anti-inflammatory mechanism is not …
including anti-inflammatory activity. However, its precise anti-inflammatory mechanism is not …
Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity
LT Zheng, J Ock, BM Kwon, K Suk - International immunopharmacology, 2008 - Elsevier
Microglia are innate immune cells in the central nervous system. Activation of microglia
plays an important role in the processes of several neurodegenerative diseases including …
plays an important role in the processes of several neurodegenerative diseases including …
[HTML][HTML] Fisetin inhibits inflammation and induces autophagy by mediating PI3K/AKT/mTOR signaling in LPS-induced RAW264. 7 cells
Y Sun, H Qin, H Zhang, X Feng, L Yang… - Food & Nutrition …, 2021 - ncbi.nlm.nih.gov
Background Fisetin, a natural potent flavonoid, has various beneficial, pharmacological
activities. In this study, we investigated expression changes of the fisetin regulating genes in …
activities. In this study, we investigated expression changes of the fisetin regulating genes in …