Despite the extensive work on pathological mechanisms and some recent advances in the
treatment of different hematological malignancies, leukemia continues to present a …

Flavonoids are a varied family of phytonutrients (plant chemicals) usually are detected in
fruits and vegetables. In this big family, there exist more than 10,000 members that is …

Flavonoids, a diverse class of polyphenolic compounds, are well known for their anticancer
properties. Moreover, it is generally accepted that these plant secondary metabolites can …

Flavonoids and their derivatives are polyphenolic secondary metabolites with an extensive
spectrum of pharmacological activities, including antioxidants, antitumor, anti-inflammatory …

To date, cytotoxic effects of flavonoids in various cancer cells are well accepted. However,
the intracellular signaling cascades triggered by these natural compounds remain largely …

A new series of chalcones, flavanones and flavones with methylenedioxy group at the 3ʹ,
4ʹ position in chalcone, 7, 8 position in flavanones and flavones with mono-, di-and …

Flavonoids, which are polyphenolic compounds, are a class of plant secondary metabolites
possessing a broad spectrum of pharmacological activity including anti-cancer activities …

The aim of this study was to identify structure elements in flavonoids that are associated with
enhanced cytotoxic activity. We determined the cytotoxicity (EC50) of 23 different flavonoids …

Background: Epidemiological studies have suggested that a regular intake of flavonoids is
beneficial for cellular homeostasis and in the prevention of the transformation of normal cells …

Cancer continues to increase global morbidity and mortality rates. Despite substantial
progress in the development of various chemically synthesized anti-cancer drugs, the poor …