Flavonoids in cancer prevention and therapy: chemistry, pharmacology, mechanisms of action, and perspectives for cancer drug discovery

GG Chabot, YS Touil, MH Pham… - … Therapies for Cancer …, 2010 - Springer
Among the numerous products available from plants, the flavonoid superfamily plays a
central role by its large number of molecules (over 6000) and also by the role these products …

Exploring the anti-breast cancer potential of flavonoid analogs

V Thakor, M Poddar, S Dey, SN Manjula… - RSC …, 2016 - pubs.rsc.org
In the course of our search for new antitumor agents for breast cancer, novel flavone
derivatives were synthesized, characterized and examined for their antitumor activities …

Flavonoids: anticancer properties

D Veeramuthu, WRT Raja, NA Al-Dhabi… - … -From biosynthesis to …, 2017 - books.google.com
Flavonoids are plant secondary metabolites. They are mainly classified into four major
groups, such as flavanols, flavones, anthocyanidins, and isoflavonoids. Furthermore, they …

Flavonoid effects on normal and leukemic cells

JL Liesveld, CN Abboud, C Lu, C McNair II, A Menon… - Leukemia Research, 2003 - Elsevier
Quercetin and flavopiridol, both flavonoids which influence oxidative milieu, proliferation,
and apoptosis of various cell types, were examined for their effects on acute myelogenous …

Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells

V Kuete, AT Mbaveng, ECN Nono, CC Simo, M Zeino… - Phytomedicine, 2016 - Elsevier
Introduction In medical oncology, multi-drug resistance (MDR) of cancer cells continues to
be a major impediment. We are in quest of novel anti-proliferative agents to overcome drug …

The antitumor activities of flavonoids

C Kanadaswami, LT Lee, PPH Lee, JJ Hwang, FC Ke… - In vivo, 2005 - iv.iiarjournals.org
The flavonoids are polyphenolic compounds found as integral components of the human
diet. They are universally present as constituents of flowering plants, particularly of food …

[HTML][HTML] Flavonoids in cancer and apoptosis

M Abotaleb, SM Samuel, E Varghese, S Varghese… - Cancers, 2018 - mdpi.com
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …

[PDF][PDF] Plant distribution and pharmacological activity of flavonoids

SH Wang, YL Hu, TX Liu - Tradit. Med. Res, 2019 - tmrjournals.com
Flavonoids are natural organic compounds that are widely found in nature, their structural
types are complex, and they mainly include flavonoids, flavonols, dihydroflavonols …

[PDF][PDF] Plant derived compounds having activity against P388 and L1210 leukemia cells

JR Patel, B Choubisa, BZ Dholakiya - J Chem Sci, 2011 - researchgate.net
Cancer is a major cause of death and the number of new cases as well as the number of
individuals living with cancer is expanding continuously. Due to the enormous propensity of …

[HTML][HTML] The anti-leukemic activity of natural compounds

C Cotoraci, A Ciceu, A Sasu, E Miutescu, A Hermenean - Molecules, 2021 - mdpi.com
The use of biologically active compounds has become a realistic option for the treatment of
malignant tumors due to their cost-effectiveness and safety. In this review, we aimed to …