Enhanced Trehalose Production Improves Growth of Escherichia coli under Osmotic Stress

JE Purvis, LP Yomano, LO Ingram - Applied and environmental …, 2005 - Am Soc Microbiol
The biosynthesis of trehalose has been previously shown to serve as an important
osmoprotectant and stress protectant in Escherichia coli. Our results indicate that …

Trehalose metabolism in Escherichia coli: stress protection and stress regulation of gene expression

AR Strom, I Kaasen - Molecular microbiology, 1993 - Wiley Online Library
Endogenously synthesized trehalose is a stress protectant in Escherichia coli. Externally
supplied trehalose does not serve as a stress protectant, but it can be utilized as the sole …

Trends in bacterial trehalose metabolism and significant nodes of metabolic pathway in the direction of trehalose accumulation

R Ruhal, R Kataria, B Choudhury - Microbial Biotechnology, 2013 - Wiley Online Library
The current knowledge of trehalose biosynthesis under stress conditions is incomplete and
needs further research. Since trehalose finds industrial and pharmaceutical applications …

Synthesis, accumulation, and excretion of trehalose in osmotically stressed Escherichia coli K-12 strains: influence of amber suppressors and function of the …

OB Styrvold, AR Strøm - Journal of bacteriology, 1991 - Am Soc Microbiol
It has been reported previously that Escherichia coli K-12 carries an amber mutation that
prevents osmotic stress-dependent accumulation of trehalose (ML Rod, KY Alam, PR …

Engineering trehalose synthesis in Lactococcus lactis for improved stress tolerance

AL Carvalho, FS Cardoso, A Bohn… - Applied and …, 2011 - Am Soc Microbiol
Trehalose accumulation is a common cell defense strategy against a variety of stressful
conditions. In particular, our team detected high levels of trehalose in Propionibacterium …

Characterization of a cytoplasmic trehalase of Escherichia coli

R Horlacher, K Uhland, W Klein, M Ehrmann… - Journal of …, 1996 - Am Soc Microbiol
Escherichia coli can synthesize trehalose in response to osmotic stress and is able to utilize
trehalose as a carbon source. The pathway of trehalose utilization is different at low and …

Biochemical and genetic characterization of osmoregulatory trehalose synthesis in Escherichia coli

HM Giaever, OB Styrvold, I Kaasen… - Journal of …, 1988 - Am Soc Microbiol
It has been shown previously that Escherichia coli accumulates endogenously synthesized
trehalose under osmotic stress. We report here that E. coli contained an osmotically …

The role of trehalose in the osmoadaptation of Escherichia coli NCIB 9484: interaction of trehalose, K+ and glutamate during osmoadaptation in continuous culture

DT Welsh, RH Reed, RA Herbert - Microbiology, 1991 - microbiologyresearch.org
Natural abundance 13C nuclear magnetic resonance spectroscopy identified the
disaccharide trehalose as the major organic osmolyte synthesized by Escherichia coli grown …

Trehalose synthesis is induced upon exposure of Escherichia coli to cold and is essential for viability at low temperatures

O Kandror, A DeLeon… - Proceedings of the …, 2002 - National Acad Sciences
Trehalose accumulates dramatically in microorganisms during heat shock and osmotic
stress and helps protect cells against thermal injury and oxygen radicals. Here we …

Trehalose-6-phosphate hydrolase of Escherichia coli

M Rimmele, W Boos - Journal of Bacteriology, 1994 - Am Soc Microbiol
The disaccharide trehalose acts as an osmoprotectant as well as a carbon source in
Escherichia coli. At high osmolarity of the growth medium, the cells synthesize large …