Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis

MM Herrmann, S Barth, B Greve… - Disease models & …, 2016 - journals.biologists.com
After encounter with a central nervous system (CNS)-derived autoantigen, lymphocytes
leave the lymph nodes and enter the CNS. This event leads only rarely to subsequent tissue …

The clinical course of experimental autoimmune encephalomyelitis is associated with a profound and sustained transcriptional activation of the genes encoding toll …

H Zekki, DL Feinstein, S Rivest - Brain pathology, 2002 - Wiley Online Library
Experimental autoimmune encephalomyelitis (EAE) is an autoimmune demyelinating
disease commonly used to model the pathogenetic mechanisms involved in multiple …

Linkage analysis of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the rat identifies a locus controlling demyelination …

I Dahlman, E Wallström, R Weissert… - Human molecular …, 1999 - academic.oup.com
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central
nervous system (CNS) with a complex etiology comprising a genetically determined …

Gene-expression profiling of the early stages of MOG-induced EAE proves EAE-resistance as an active process

E Mix, S Ibrahim, J Pahnke, D Koczan, C Sina… - Journal of …, 2004 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) induced by myelin oligodendrocyte
glycoprotein (MOG) is a well-established animal model of multiple sclerosis (MS) in rodents …

Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune …

DA Brown, PE Sawchenko - Journal of Comparative Neurology, 2007 - Wiley Online Library
Murine models of experimental autoimmune encephalomyelitis (EAE) are important vehicles
for studying the effects of genetic manipulation on disease processes related to multiple …

Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of …

M Evangelidou, M Karamita, SS Vamvakas… - The Journal of …, 2014 - journals.aai.org
Experimental autoimmune encephalomyelitis (EAE) is a valuable model for studying
immunopathology in multiple sclerosis (MS) and for exploring the interface between …

Antibody response in MOG35–55 induced EAE

PH Lalive, N Molnarfi, M Benkhoucha… - Journal of …, 2011 - Elsevier
Neurological deficit in experimental autoimmune encephalomyelitis (EAE) and multiple
sclerosis is widely considered to be a consequence of synergistic T and B cell responses to …

[HTML][HTML] Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete …

SA Jagessar, N Heijmans, ELA Blezer, J Bauer… - Journal of …, 2015 - Springer
Background Experimental autoimmune encephalomyelitis (EAE) in the common marmoset
monkey (Callithrix jacchus) is a relevant preclinical model for translational research into …

Focal experimental autoimmune encephalomyelitis in the Lewis rat induced by immunization with myelin oligodendrocyte glycoprotein and intraspinal injection of …

M Sasaki, KL Lankford, RJ Brown, NH Ruddle… - Glia, 2010 - Wiley Online Library
Various models of experimental autoimmune encephalomyelitis (EAE) have led to insights
into the pathogenesis and novel therapies for multiple sclerosis. One generalized EAE …

Characterization of Multiple Sclerosis candidate gene expression kinetics in rat experimental autoimmune encephalomyelitis

MT Hedreul, A Gillett, T Olsson, M Jagodic… - Journal of …, 2009 - Elsevier
The immunological mechanisms underlying autoimmunity are being elucidated through
genetic and functional analyses in both humans and rodent models. However, acceptance …