Liver X receptors (LXRs) are master regulators of cholesterol homeostasis and inflammation
in the central nervous system (CNS). The brain, which contains a disproportionately large …

Liver X Receptors (LXR) alpha and beta are two members of nuclear receptor superfamily
documented as endogenous cholesterol sensors. Following conversion of cholesterol in …

Liver X receptors (LXRα and LXRβ) are oxysterol receptors that function as master
transcription factors mediating cholesterol homeostasis in the periphery. LXRs regulate the …

Liver X receptors (LXRα and-β) are nuclear receptors abundant in the liver where they are
regulators of lipid homeostasis. Both LXRs are also expressed in the brain, but their roles in …

Liver X receptors (LXR) are nuclear receptors that have emerged as key regulators of lipid
metabolism. In addition to their functions as cholesterol sensors, LXR have also been found …

The nuclear oxysterol receptors liver X receptor-α [LXRα (NR1H3)] and LXRβ (NR1H2)
coordinately regulate genes involved in cholesterol homeostasis. Although both LXR …

Liver X receptors (LXRs) are nuclear receptors involved in the regulation of lipid metabolism
and inflammatory responses in the central nervous system. Defects in cholesterol …

The liver X receptors (LXRs) are pivotal regulators of lipid homeostasis in mammals. These
transcription factors control the expression of a battery of genes involved in the uptake …

Although cholesterol is a major component of the CNS, there is little information on how or
whether a change in sterol flux across the blood–brain barrier might alter …

Liver X receptor (LXR) α and β are nuclear receptors that control cellular metabolism. LXRs
modulate the expression of genes involved in cholesterol and lipid metabolism in response …