Sleep is essential for basic survival as well as for optimal physical and cognitive
performance in both human beings and animals. To investigate the effect of syringin on …

The sleep-promoting effect of isoliquiritigenin (ILTG) was investigated by analyzing the sleep
architecture in mice. A hypnotic diazepam (DZP, 2 mg/kg) significantly decreased sleep …

Background Most mammalian cells harbor molecular circadian clocks that synchronize
physiological functions with the 24-h day-night cycle. Disruption of circadian rhythms …

The effects of the Eurycoma longifolia (also known as Tongkat Ali [TA]) on sleep and
wakefulness was evaluated in C57BL/6 mice. While TA has been used as an aphrodisiac in …

Cordycepin (3′‐deoxyadenosine) is a naturally occurring adenosine analogue and one of
the bioactive constituents isolated from Cordyceps militaris/Cordyceps sinensis, species of …

With an astounding 10% to 15% of the United States population meeting criteria for an
insomnia disorder, 1, 2 insomnia is not only the most common sleep disorder in the …

Progress has been made in the elucidation of sleep and wakefulness regulation at the
neurocircuit level,. However, the intracellular signalling pathways that regulate sleep and the …

Ketamine, a drug with rapid antidepressant effects and well-described effects on slow wave
sleep (SWS), is a useful intervention for investigating sleep–wake mechanisms involved in …

Background: Uncaria rhynchophylla (Miq.) Jacks (Rubinaceae), a common herbal medicine
known as Gou-teng in Chinese, is commonly used in Chinese medicine practice for the …

Rhynchophylline (RIN) and isorhynchophylline (IRN), two of the representative types of
indole alkaloids, showed the unique spiroindole structures produced in Uncaria …